Recombinant Anti-CXCR3 (AA 1-15 x AA 16-30) Biparatopic Antibody, Tandem scFv (Clone 1C6 x Clone 4B4) (CAT#: VS-0525-YC38)

• Host Animal 1
• Mouse

• Host Animal 2
• Mouse

• Specificity
• Human CXCR3

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Clone 1
• 1C6

• Clone 2
• 4B4

• Epitope 1
• aa 1-15

• Epitope 2
• aa 16-30

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA, FC

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• C-X-C Motif Chemokine Receptor 3

• Introduction
• This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4.

• Alternative Names
• Chemokine (C-X-C Motif) Receptor 3; G Protein-Coupled Receptor 9; Interferon-Inducible Protein 10 Receptor; IP-10 Receptor; CKR-L2; GPR9; CD183 Antigen; Mig Receptor; CMKAR3; IP10-R; CXC-R3; CXCR-3; CD182; CD183; Mig-R; MigR

• Gene ID
• 2833

• UniProt ID
• P49682

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