This product is a recombinant antibody that recognizes CXCR4. The monoclonal antibody C-9P21 reacts with the epitope of CXCR4. The antibody is capable of inhibiting the binding of a ligand to CXCR4.
Figure 1 shows inhibition of ligand (SDF-1α) induced cell migration by anti-CXCR4 scFv C-9P21.
Human T-cell leukaemia CCRF-CEM cells labelled with BATDA were induced to migrate in Boyden chambers, where the SDF-1 ligand was placed in the lower chamber and the cells were co-incubated with antibodies or medium only as a control in the upper chambers.
Figure 2 show the results of an assay to test the ability of the antibodies B-1M22, C-9P21, C-1I24, and D-1K21 to induce CDC.
Figure 3 shows the induction of ADCC by the anti-CXCR4 antibodies B-1M22, C-9P21, C-1I24, and D-1K21.
Dose-response killing of CCRF-CEM cells is shown for scFvs C-9P21.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0011CL-F(E) | Anti-Human CXCR4 Recombinant Antibody Fab Fragment (414H5) | FC, IHC, Block, Inhib, FuncS | |
TAB-0012CL-F(E) | Anti-Human CXCR4 Recombinant Antibody Fab Fragment (515H7) | FC, IHC, Block, Inhib, FuncS | |
TAB-143MZ-S(P) | Mouse Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-143MZ-S(P)) | cAMP Assay | Mouse scFv |
TAB-144MZ-S(P) | Mouse Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-144MZ-S(P)) | cAMP Assay | Mouse scFv |
TAB-145MZ-S(P) | Mouse Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-145MZ-S(P)) | cAMP Assay | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-150MZ | Anti-Human CXCR4 Recombinant Antibody (CF172) | FC | Human antibody |
TAB-151MZ | Anti-Human CXCR4 Recombinant Antibody (5C9) | FuncS | Human antibody |
TAB-152MZ | Anti-Human CXCR4 Recombinant Antibody (5E1) | FuncS | Human antibody |
TAB-153MZ | Anti-Human CXCR4 Recombinant Antibody (7C8) | FuncS, Inhib | Human antibody |
TAB-154MZ | Anti-Human CXCR4 Recombinant Antibody (6C7) | Block, FuncS, Inhib | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-146MZ-S(P) | Human Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-146MZ-S(P)) | cAMP Assay | Humanized scFv |
TAB-147MZ-S(P) | Human Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-147MZ-S(P)) | cAMP Assay | Humanized scFv |
TAB-148MZ-S(P) | Human Anti-CXCR4 Recombinant Antibody; scFv Fragment (TAB-148MZ-S(P)) | cAMP Assay | Humanized scFv |
TAB-146MZ-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (TAB-146MZ-F(E)) | cAMP Assay | Humanized Fab |
TAB-147MZ-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (TAB-147MZ-F(E)) | cAMP Assay | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0152MZ | Chicken Anti-CXCR4 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-684CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone 12G5) | FC, CyTOF®, Neut | Mouse IgG2a |
NEUT-685CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone 12G5R) | FC, Neut | Mouse IgG2a |
NEUT-687CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone CBL046) | FC, IHC, Neut | Mouse IgG2 |
NEUT-688CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone CBL470) | FC, CyTOF®, Neut | Mouse IgG2b |
NEUT-689CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone CBL783) | Neut | Mouse IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-686CQ | Mouse Anti-CXCR4 Recombinant Antibody (clone 44716.111) | FC, ICC, IF, IHC-P, Inhib | Mouse IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0889 | Hi-Affi™ Rabbit Anti-CXCR4 Recombinant Antibody (clone DS889AB) | WB, IHC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0044-YC | Human Anti-CXCR4 Recombinant Antibody (clone hz515H7VH1D76NVL2) | Block, Cyt, FC | Humanized IgG1, κ |
HPAB-0045-YC | Human Anti-CXCR4 Recombinant Antibody (HPAB-0045-YC) | FC, Cyt | Humanized IgG |
MRO-1796-CN | Rabbit Anti-CXCR4 Polyclonal Antibody (MRO-1796-CN) | WB, IF, IHC, FC | Rabbit IgG |
HPAB-0685-WJ | Human Anti-CXCR4 Recombinant Antibody (HPAB-0685-WJ) | FC | Human IgG |
HPAB-0686-WJ | Human Anti-CXCR4 Recombinant Antibody (HPAB-0686-WJ) | FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0659-CN-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (HPAB-0659-CN-F(E)) | FC, Neut | Human Fab |
HPAB-0660-CN-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (HPAB-0660-CN-F(E)) | FC, Neut | Human Fab |
HPAB-0661-CN-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (HPAB-0661-CN-F(E)) | FC, Neut | Human Fab |
HPAB-0685-WJ-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (HPAB-0685-WJ-F(E)) | FC | Human Fab |
HPAB-0686-WJ-F(E) | Human Anti-CXCR4 Recombinant Antibody; Fab Fragment (HPAB-0686-WJ-F(E)) | FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H72 | Afuco™ Anti-CXCR4 ADCC Recombinant Antibody (Ulocuplumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0329-WJ-S(P) | Mouse Anti-CXCR4 Recombinant Antibody; scFv Fragment (HPAB-0329-WJ-S(P)) | ELISA, FC, IHC | Mouse scFv |
HPAB-0334-WJ-S(P) | Mouse Anti-CXCR4 Recombinant Antibody (clone 4C1); scFv Fragment | ELISA, WB | Mouse scFv |
HPAB-1504-FY-F(E) | Human Anti-CXCR4 Recombinant Antibody (clone C-9P21); scFv Fragment | ELISA, Inhib | Human scFv |
HPAB-1505-FY-F(E) | Human Anti-CXCR4 Recombinant Antibody (clone B-1M2); scFv Fragment | ELISA, Inhib | Human scFv |
HPAB-1506-FY-F(E) | Human Anti-CXCR4 Recombinant Antibody (clone C-1I24); scFv Fragment | ELISA, Inhib | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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