Human Anti-CXCR4 Recombinant Antibody (clone C-1I24) (CAT#: HPAB-1506-FY)

This product is a recombinant antibody that recognizes CXCR4. The monoclonal antibody C-1I24 reacts with the epitope of CXCR4. The antibody is capable of inhibiting the binding of a ligand to CXCR4.


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Cyt

Figure 1 shows the induction of ADCC by the anti-CXCR4 antibodies B-1M22, C-9P21, C-1I24, and D-1K21.

Figure 1 shows the induction of ADCC by the anti-CXCR4 antibodies B-1M22, C-9P21, C-1I24, and D-1K21.

Dose-response killing of CCRF-CEM cells is shown for IgGs C-1I24.

Cyt

Figure 2 show the results of an assay to test the ability of the antibodies B-1M22, C-9P21, C-1I24, and D-1K21 to induce CDC.

Figure 2 show the results of an assay to test the ability of the antibodies B-1M22, C-9P21, C-1I24, and D-1K21 to induce CDC.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1
  • Specificity
  • Human CXCR4
  • Species Reactivity
  • Human
  • Clone
  • C-1I24
  • Applications
  • ELISA, Inhib

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The CXCR4 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition, Cytotoxicity.

Target

  • Alternative Names
  • C-X-C Motif Chemokine Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; Chemokine (C-X-C Motif) Receptor 4; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; Fusin; LAP-3; LESTR; NPYRL; FB22; HM89; LCR1; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin)

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Chicken IgY Antibody

CAT Product Name Application Type
BRD-0152MZ Chicken Anti-CXCR4 Polyclonal IgY WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-686CQ Mouse Anti-CXCR4 Recombinant Antibody (clone 44716.111) FC, ICC, IF, IHC-P, Inhib Mouse IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0889 Hi-Affi™ Rabbit Anti-CXCR4 Recombinant Antibody (clone DS889AB) WB, IHC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H72 Afuco™ Anti-CXCR4 ADCC Recombinant Antibody (Ulocuplumab), ADCC Enhanced IP, IF, FuncS, FC, Neut, ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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