Mouse Anti-DAG1 Recombinant Antibody (clone P38G1) (CAT#: VS11-QX58)
This product is a recombinant mouse antibody that binds human and mouse beta dystroglycan (β-DAG). This antibody can be used for the following applications: ELISA, FC.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70563/1346_G10_2_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70563/1346_G10_2_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_B_9_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_B_9_5.jpg
Figure 4 High expression in placenta.
(Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_A_3_7.jpg
(Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_A_3_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (BEWO)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173402-DAG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173402-DAG1
Specifications
- Immunogen
- A mixture of transfected HEK 293 cells expressing human and mouse β-DAG.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human and mouse beta dystroglycan
- Species Reactivity
- Human, Mouse
- Clone
- P38G1
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Dystroglycan 1 (Dystrophin-Associated Glycoprotein 1); Dystrophin-Associated Glycoprotein-1; Dystrophin-Associated Glycoprotein 1; Alpha-Dystroglycan; Beta-Dystroglycan; MDDGC7; 156DAG; MDDGC9; AGRNR; A3A; DAG
- Gene ID
- 1605
- UniProt ID
- Q14118
- Long Name
- Dystroglycan 1
- Cellular Localization
- Nucleoplasm, Vesicles, Plasma membrane
- Function
- The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. [Alpha-dystroglycan]: Extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3965z | Mouse Anti-DAG1 Recombinant Antibody (clone 41C1) | IHC, WB, ELISA, FuncS | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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