Mouse Anti-DAG1 Recombinant Antibody (clone P38G1) (CAT#: VS11-QX58)
This product is a recombinant mouse antibody that binds human and mouse beta dystroglycan (β-DAG). This antibody can be used for the following applications: ELISA, FC.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70563/1346_G10_2_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70563/1346_G10_2_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_B_9_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_B_9_5.jpg
Figure 4 High expression in placenta.
(Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_A_3_7.jpg
(Trophoblastic cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1960/5470_A_3_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (BEWO)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173402-DAG1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173402-DAG1
Specifications
- Immunogen
- A mixture of transfected HEK 293 cells expressing human and mouse β-DAG.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human and mouse beta dystroglycan
- Species Reactivity
- Human, Mouse
- Clone
- P38G1
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Dystroglycan 1 (Dystrophin-Associated Glycoprotein 1); Dystrophin-Associated Glycoprotein-1; Dystrophin-Associated Glycoprotein 1; Alpha-Dystroglycan; Beta-Dystroglycan; MDDGC7; 156DAG; MDDGC9; AGRNR; A3A; DAG
- Gene ID
- 1605
- UniProt ID
- Q14118
- Long Name
- Dystroglycan 1
- Cellular Localization
- Nucleoplasm, Vesicles, Plasma membrane
- Function
- The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. [Alpha-dystroglycan]: Extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3965z | Mouse Anti-DAG1 Recombinant Antibody (clone 41C1) | IHC, WB, ELISA, FuncS | Mouse IgG2b |
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