AbPlus™ Anti-DAP3 Magnetic Beads (VS-0724-YC913)

CAT#: VS-0724-YC913

The AbPlus Anti-DAP3 Magnetic Beads (VS-0724-YC913) is an innovative affinity resin which is bound with anti-DAP3 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of DAP3 protein under native and denaturing conditions.

Gene Expression
Figure 1 IHC staining of human duodenum Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Kidney Figure 5 Testis Figure 6 Placenta Figure 7 Lymph node Figure 8 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-DAP3 specific antibody
  • Target
  • DAP3
  • Immunogen
  • Synthetic peptide corresponding to the C-terminus of the human DAP3.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
  • Alternative Names
  • Death Associated Protein 3; Mitochondrial Small Ribosomal Subunit Protein MS29; Ionizing Radiation Resistance Conferring Protein; Mitochondrial 28S Ribosomal Protein S29; MRP-S29; MRPS29;
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