Mouse Anti-DCT Recombinant Antibody (clone 2A10)
CAT#: VS3-WK1589
This antibody is a mouse recombinant antibody against human DCT, which The clone 2A10 can be used in WB analysis at a dilution of 1/1000-1/2000 and IHC analysis at a dilution of 1/50-1/200.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10742/1844_A3_33_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10743/ihc_selected.jpg
Normal Tissue
Figure 3 Skin
Melanocytes Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10743/26206_B_9_1.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000080166-DCT
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Specifications
- Immunogen
- Synthesized peptide derived from human TRP2 DCT
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human DCT
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 2A10
- Applications
- IHC-P, WB
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 0.5% BSA, 50% Glycerol
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC-P: 1/50-1/200
WB: 1/1000-1/2000
Target
- Alternative Names
- Dopachrome Tautomerase; L-Dopachrome Delta-Isomerase; Dopachrome Delta-Isomerase; Tyrosine-Related Protein 2; L-Dopachrome Isomerase; EC 5.3.3.12; TYRP2; TRP-2
- Gene ID
- 1638
- UniProt ID
- P40126
- Long Name
- Dopachrome Tautomerase
- Sequence Similarities
- Belongs to the tyrosinase family.
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylated.
- Protein Refseq
- NP_001123361.1
- Function
- Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
Isotype Control
- CAT
- Product Name
See other products for "DCT"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2021z | Mouse Anti-DCT Recombinant Antibody (clone 20B5) | WB, ELISA, IF, IP | Mouse IgG1, κ |
| VS13-YC288 | Rabbit Anti-DCT Recombinant Antibody (VS13-YC288) | IHC-P | Rabbit IgG |
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