This product is a recombinant antibody that recognizes DLL4. The monoclonal antibody 61B reacts with the epitope of DLL4.
Figure 1 61B has no cross-reactivity to mouse Dll4.
The bound AP fusion proteins were detected using AP substrate and a plate reader. Experiment was performed in triplicate. Data are presented as mean ±SEM.
Zhou, B., Wang, H., Liu, R., Wang, M., Deng, H., Giglio, B. C., ... & Li, Z. (2015). PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular pharmaceutics, 12(10), 3527-3534.
Figure 2 Confocal fluorescence images of 61B-Cy5.5 and immunofluorescence staining of CD31 in HT29 tumor tissues.
Images were obtained under identical conditions and displayed at same magnification. Scale bar = 100 μm.
Zhou, B., Wang, H., Liu, R., Wang, M., Deng, H., Giglio, B. C., ... & Li, Z. (2015). PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular pharmaceutics, 12(10), 3527-3534.
Figure 3 IF result of 61B antibody.
61B-Alexa Fluor555 staining of U87MG cells in the absence (upper panel) and presence (lower panel) of excess amount of un-labeled 61B antibody.
Zhou, B., Wang, H., Liu, R., Wang, M., Deng, H., Giglio, B. C., ... & Li, Z. (2015). PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using 64Cu-Labeled Monoclonal Antibody 61B. Molecular pharmaceutics, 12(10), 3527-3534.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-204 | Anti-Human DLL4 Recombinant Antibody (Demcizumab) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG2 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-217CL | Human Anti-DLL4 Recombinant Antibody (TAB-217CL) | WB, IHC, IF, FC, Inhib | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-216MZ | Mouse Anti-DLL4 Recombinant Antibody (TAB-216MZ) | FC, FuncS | Mouse IgG |
TAB-227MZ-S(P) | Anti-Human DLL4 Recombinant Antibody scFv Fragment (1C1) | ELISA, FC | |
TAB-232MZ-S(P) | Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-232MZ-S(P)) | ELISA, FC | Rat scFv |
TAB-233MZ-S(P) | Rat Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-233MZ-S(P)) | ELISA, FC | Rat scFv |
TAB-216MZ-F(E) | Mouse Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-216MZ-F(E)) | FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-217MZ | Human Anti-DLL4 Recombinant Antibody (TAB-217MZ) | FC, FuncS | Chimeric (mouse/human) IgG |
TAB-217MZ-S(P) | Mouse Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-217MZ-S(P)) | FC | Mouse scFv |
TAB-217MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-217MZ-F(E)) | FC | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-218MZ | Human Anti-DLL4 Recombinant Antibody (TAB-218MZ) | ELISA, FC, Neut | Human IgG |
TAB-219MZ | Human Anti-DLL4 Recombinant Antibody (TAB-219MZ) | ELISA, FC, Neut, WB | Human IgG |
TAB-220MZ | Human Anti-DLL4 Recombinant Antibody (TAB-220MZ) | ELISA, FC, Neut | Human IgG |
TAB-221MZ | Human Anti-DLL4 Recombinant Antibody (TAB-221MZ) | ELISA, FC, Neut | Human IgG |
TAB-222MZ | Human Anti-DLL4 Recombinant Antibody (TAB-222MZ) | Block, FC, FuncS, Inhib | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-707CQ | Hamster Anti-Dll4 Recombinant Antibody (clone HMD4-2) | Block | Hamster IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4140 | Hi-Affi™ Rabbit Anti-DLL4 Recombinant Antibody (clone SI213DS) | ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0203-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0203-CN) | ELISA, WB, FC, IP | Human IgG1 |
HPAB-0204-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0204-CN) | ELISA, WB, FC, IP | Human IgG1 |
HPAB-0205-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0205-CN) | ELISA, WB, FC, IP | Human IgG4 |
HPAB-0206-CN | Mouse Anti-DLL4 Recombinant Antibody (HPAB-0206-CN) | ELISA, WB, FC, IHC, IF, ICC | Mouse IgG2 |
HPAB-0208-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0208-CN) | ELISA, WB, FC, IHC, IF, ICC | Humanized IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0075-CN-S(P) | Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0075-CN-S(P)) | ELISA, WB, FC | Human scFv |
HPAB-0076-CN-S(P) | Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0076-CN-S(P)) | ELISA, WB, FC | Human scFv |
HPAB-0211-WJ-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone MMGZ01); scFv Fragment | ELISA | Mouse scFv |
HPAB-0716-FY-F(E) | Mouse Anti-DLL4 Recombinant Antibody (clone AB015); scFv Fragment | FC | Mouse scFv |
HPAB-1108-FY-F(E) | Human Anti-DLL4 Recombinant Antibody (clone 61B); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0203-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0203-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
HPAB-0204-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0204-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
HPAB-0205-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0205-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
HPAB-0206-CN-F(E) | Mouse Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0206-CN-F(E)) | ELISA, WB, FC, IHC, IF, ICC | Mouse Fab |
HPAB-0208-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0208-CN-F(E)) | ELISA, WB, FC, IHC, IF, ICC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-204 | Afuco™ Anti-DLL4 ADCC Recombinant Antibody (Demcizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1512-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (56A09) | Block, ELISA, FC | Llama VHH |
HPAB-1513-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (56H08) | Block, ELISA, FC | Llama VHH |
HPAB-1514-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (104G01) | Block, ELISA, FC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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