Mouse Anti-DLL4 Recombinant Antibody (clone MMGZ01); scFv Fragment (CAT#: HPAB-0211-WJ-S(P))
This product is a mouse antibody targeting human DLL4 with high affinity and biological activity. This antibody can be combined with rhDll4 specifically, and can block human umbilical vein endothelial cells (HUVEC) proliferation suppression of the rhDll4.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_2_selected.jpg
(Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_2_selected.jpg
Figure 2 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_9_3.jpg
Figure 3 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_4.jpg
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_4.jpg
Figure 4 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_8_5.jpg
Figure 5 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23392/51479_A_4_6.jpg
Figure 6 RNA cell line category: Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128917-DLL4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128917-DLL4
Specifications
- Immunogen
- Recombinant human DLL4 protein
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human DLL4
- Species Reactivity
- Human
- Clone
- MMGZ01
- Applications
- ELISA
- Related Disease
- Cancers
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- DLL4; delta-like 4 (Drosophila); delta like 4 homolog (Drosophila); delta-like protein 4; delta4
- Gene ID
- 54567
- UniProt ID
- Q9NR61
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone MMGZ01"
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-204 | Anti-Human DLL4 Recombinant Antibody (Demcizumab) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG2 - kappa |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-217CL | Human Anti-DLL4 Recombinant Antibody (TAB-217CL) | WB, IHC, IF, FC, Inhib | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-216MZ | Mouse Anti-DLL4 Recombinant Antibody (TAB-216MZ) | FC, FuncS | Mouse IgG |
| TAB-227MZ-F(E) | Anti-Human DLL4 Recombinant Antibody Fab Fragment (1C1) | ELISA, FC | |
| TAB-232MZ-F(E) | Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-232MZ-F(E)) | ELISA, FC | Rat Fab |
| TAB-233MZ-F(E) | Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-233MZ-F(E)) | ELISA, FC | Rat Fab |
| TAB-234MZ-F(E) | Rat Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-234MZ-F(E)) | ELISA, FC | Rat Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-217MZ | Human Anti-DLL4 Recombinant Antibody (TAB-217MZ) | FC, FuncS | Chimeric (mouse/human) IgG |
| TAB-217MZ-S(P) | Mouse Anti-DLL4 Recombinant Antibody; scFv Fragment (TAB-217MZ-S(P)) | FC | Mouse scFv |
| TAB-217MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-217MZ-F(E)) | FC | Chimeric antibody (mouse/human) |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-218MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-218MZ-F(E)) | ELISA, FC | Human Fab |
| TAB-219MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-219MZ-F(E)) | ELISA, FC | Human Fab |
| TAB-220MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-220MZ-F(E)) | ELISA, FC | Human Fab |
| TAB-221MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-221MZ-F(E)) | ELISA, FC | Human Fab |
| TAB-222MZ-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (TAB-222MZ-F(E)) | FC | Human Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-707CQ | Hamster Anti-Dll4 Recombinant Antibody (clone HMD4-2) | Block | Hamster IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4140 | Hi-Affi™ Rabbit Anti-DLL4 Recombinant Antibody (clone SI213DS) | ELISA | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0203-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0203-CN) | ELISA, WB, FC, IP | Human IgG1 |
| HPAB-0204-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0204-CN) | ELISA, WB, FC, IP | Human IgG1 |
| HPAB-0207-CN | Human Anti-DLL4 Recombinant Antibody (HPAB-0207-CN) | ELISA, WB, FC, IHC, IF, ICC | Chimeric (mouse/human) IgG1, κ |
| VS3-XY583 | Mouse Anti-DLL4 Recombinant Antibody (clone 4A11F8) | ELISA, WB, IHC | Mouse IgG1 |
| VS3-XY584 | Mouse Anti-DLL4 Recombinant Antibody (clone 4A11) | ELISA, WB, FC | Mouse IgG2b |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0075-CN-S(P) | Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0075-CN-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0076-CN-S(P) | Human Anti-DLL4 Recombinant Antibody; scFv Fragment (HPAB-0076-CN-S(P)) | ELISA, WB, FC | Human scFv |
| HPAB-0152-LSX-S(P) | Mouse Anti-DLL4 Recombinant Antibody (clone 21H3); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1108-FY-F(E) | Human Anti-DLL4 Recombinant Antibody (clone 61B); scFv Fragment | ELISA | Human scFv |
| HPAB-1109-FY-F(E) | Human Anti-DLL4 Recombinant Antibody (clone 2-6); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0203-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0203-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
| HPAB-0204-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0204-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
| HPAB-0205-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0205-CN-F(E)) | ELISA, WB, FC, IP | Human Fab |
| HPAB-0206-CN-F(E) | Mouse Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0206-CN-F(E)) | ELISA, WB, FC, IHC, IF, ICC | Mouse Fab |
| HPAB-0208-CN-F(E) | Human Anti-DLL4 Recombinant Antibody; Fab Fragment (HPAB-0208-CN-F(E)) | ELISA, WB, FC, IHC, IF, ICC | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-204 | Afuco™ Anti-DLL4 ADCC Recombinant Antibody (Demcizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1512-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (56A09) | Block, ELISA, FC | Llama VHH |
| HPAB-1513-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (56H08) | Block, ELISA, FC | Llama VHH |
| HPAB-1514-FY | Recombinant Llama Anti-DLL4 Single Domain Antibody (104G01) | Block, ELISA, FC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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