This product is a recombinant mouse antibody clone BM9-7, which specifically binds to DNA.
Figure 1 Comparisons of dsDNA-binding activities between clonally related IgG2b anti-DNA mAb.
dsDNA-binding activities were examined using synthetic dsDNA-coupled silica gel particles and flow cytometry. Each dsDNA-coupled particle was first stained with culture supernatant of mAb at given Ig concentrations and then stained with FITC-labeled anti-mouse Ig antibodies. dsDNA-binding activities were expressed by mean channels of fluorescence intensity.
Miyazaki, S., Shimura, J., Hirose, S., Sanokawa, R., Tsurui, H., Wakiya, M., ... & Shirai, T. (1997). Is structural flexibility of antigen-binding loops involved in the affinity maturation of anti-DNA antibodies?. International immunology, 9(5), 771-777.
Figure 2 Comparison of the flexibility of Fv loops during molecular dynamics, as determined by cluster graphs.
Coordinates of all atoms were obtained at the time interval of 500 fs during the simulation period of 50 ps, each set of coordinates was saved as a frame and 100 frames were stored in chronological order. The extent of protein motions seen in the simulations was estimated by calculating the root mean square fluctuations of all atomic positions including side chains among 100 frames. Results are displayed in cluster graph, in which ranges of root mean square values of 0.00–1.00 Å are shown in the black area and those of .1.00 Å are in the white area.
Miyazaki, S., Shimura, J., Hirose, S., Sanokawa, R., Tsurui, H., Wakiya, M., ... & Shirai, T. (1997). Is structural flexibility of antigen-binding loops involved in the affinity maturation of anti-DNA antibodies?. International immunology, 9(5), 771-777.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABW-032 | Recombinant Mouse Anti-DNA Antibody (ED10) | WB, ELISA | IgG |
PABC-033 | Mouse Anti-DNA Recombinant Antibody (clone 64M-2) | ELISA, WB | Mouse IgG |
PABL-451 | Mouse Anti-DNA Recombinant Antibody (clone A52) | ELISA, WB, FuncS | Mouse IgG |
FAMAB-0075CQ | Mouse Anti-DNA Recombinant Antibody (clone 16-13) | ELISA | Mouse IgG2a |
FAMAB-0076CQ | Mouse Anti-DNA Recombinant Antibody (clone 1A11) | ELISA | Mouse IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-048 | Recombinant Mouse Anti-DNA Antibody | WB, ELISA, FuncS | IgG |
PABX-048-F (E) | Recombinant Mouse Anti-DNA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-048-S (P) | Recombinant Mouse Anti-DNA Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0086-YC-F(E) | Mouse Anti-DNA Recombinant Antibody (clone H149); Fab Fragment | ELISA, IF | Mouse Fab |
FAMAB-0087-YC-F(E) | Mouse Anti-DNA Recombinant Antibody (clone F11); Fab Fragment | ELISA, IF | Mouse Fab |
FAMAB-0088-YC-F(E) | Mouse Anti-DNA Recombinant Antibody (clone 17s.128); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0089-YC-F(E) | Mouse Anti-DNA Recombinant Antibody (clone PL9-6); Fab Fragment | ELISA, IF | Mouse Fab |
FAMAB-0090-YC-F(E) | Mouse Anti-DNA Recombinant Antibody (clone PL9-11); Fab Fragment | ELISA, IF | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0092CQ-S(P) | Mouse Anti-DNA Recombinant Antibody (clone DP11); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0093CQ-S(P) | Mouse Anti-DNA Recombinant Antibody (clone DP17); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0036WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone T33-17); scFv Fragment | WB | Human scFv |
FAMAB-0046WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone O-81); scFv Fragment | WB | Human scFv |
FAMAB-0066JF-S(P) | Mouse Anti-DNA Recombinant Antibody (clone 4B2); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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