Recombinant monoclonal antibody can sepecially bind to dsDNA and ssDNA. This anti-DNA antibody 4B2 is useful in elucidating the nature of anti-DNA–induced renal damage in SLE.
Figure 1 Inhibition of R4A binding to selected phage by calf thymus dsDNA.
R4A selected phage clones containing the consensus motif to which R4A showed binding by ELISA.
Gaynor, B., Putterman, C., Valadon, P., Spatz, L., Scharff, M. D., & Diamond, B. (1997). Peptide inhibition of glomerular deposition of an anti-DNA antibody. Proceedings of the National Academy of Sciences, 94(5), 1955-1960.
Figure 2 52b3 binding by ELISA to various phage clones.
OD after addition of substrate was monitored at 405 nm.
Gaynor, B., Putterman, C., Valadon, P., Spatz, L., Scharff, M. D., & Diamond, B. (1997). Peptide inhibition of glomerular deposition of an anti-DNA antibody. Proceedings of the National Academy of Sciences, 94(5), 1955-1960.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-074 | Mouse Anti-DNA Recombinant Antibody; Fab Fragment (PFBL-074) | ELISA, WB, FuncS | Mouse Fab |
PFBL-075 | Mouse Anti-DNA Recombinant Antibody (clone ED10); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
PFBW-032 | Recombinant Mouse Anti-DNA Antibody Fab Fragment (ED10) | WB, ELISA | IgG |
PFBC-033 | Mouse Anti-DNA Recombinant Antibody (clone 64M-2); Fab Fragment | ELISA, WB | Mouse Fab |
PFBL-448 | Mouse Anti-DNA Recombinant Antibody (clone A52); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABW-032 | Recombinant Mouse Anti-DNA Antibody (ED10) | WB, ELISA | IgG |
PABC-033 | Mouse Anti-DNA Recombinant Antibody (clone 64M-2) | ELISA, WB | Mouse IgG |
FAMAB-0086YC | Mouse Anti-DNA Recombinant Antibody (clone H149) | ELISA, IF | Mouse IgM, κ |
FAMAB-0087YC | Mouse Anti-DNA Recombinant Antibody (clone F11) | ELISA, IF | Mouse IgG |
FAMAB-0088YC | Mouse Anti-DNA Recombinant Antibody (clone 17s.128) | ELISA | Mouse IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-033 | Mouse Anti-DNA Recombinant Antibody (clone 64M-2); scFv Fragment | ELISA, WB | Mouse scFv |
HPAB-0131-YJ-S(P) | Mouse Anti-DNA Recombinant Antibody; scFv Fragment (HPAB-0131-YJ-S(P)) | IHC, FuncS | Mouse scFv |
HPAB-0132-YJ-S(P) | Human Anti-DNA Recombinant Antibody; scFv Fragment (HPAB-0132-YJ-S(P)) | IHC, FuncS | Human scFv |
FAMAB-0036WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone T33-17); scFv Fragment | WB | Human scFv |
FAMAB-0046WJ-S(P) | Human Anti-DNA Recombinant Antibody (clone O-81); scFv Fragment | WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-048 | Recombinant Mouse Anti-DNA Antibody | WB, ELISA, FuncS | IgG |
PABX-048-F (E) | Recombinant Mouse Anti-DNA Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-048-S (P) | Recombinant Mouse Anti-DNA Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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