Human Anti-DSG2 Recombinant Antibody (HPAB-0405-FY)
CAT#: HPAB-0405-FY
This product is a recombinant Human antibody that recognizes DSG2. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/1685_D1_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/672_G5_4_selected.jpg
Normal Tissue
Figure 3 Rectum
High expression in rectum
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4896/15170_A_6_3_val_selected.jpg
Normal Tissue
Figure 4 Small intestine
High expression in small intestine
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_6_2_val_selected.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_8_5.jpg
Normal Tissue
Figure 6 Parathyroid gland
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25122/55672_A_1_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (CAPAN-2, HaCaT, HBEC3-KT, hTERT-HME1, OE19)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000046604-DSG2
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Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human DSG2
- Species Reactivity
- Human
- Applications
- FC, IP
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Simple to Utilize
This antibody is simple to use and includes a comprehensive how-to manual. I have performed assays on every sample, and the results are quite consistent and repeatable.
Cost-effective
Considering its effectiveness and quality, this antibody offers great value for the money. In a range of research applications, it fulfilled every one of my expectations. Strongly advised!
Light Background
This antibody stands out in part because of how little background it leaves in tests. Because of the precise and lucid data it produces, analysis is reliable and easy.
Q&As
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How can I reduce my samples' proteolytic degradation?
A: To prevent proteolytic degradation, add protease inhibitors to your lysis buffers and keep samples on ice throughout processing.
-
Why is antibody validation important?
A: Validation ensures that the antibody binds specifically to its target epitope, resulting in consistent and reproducible findings across multiple trials and settings.
-
Can the initial antibodies be reused in experiments?
A: Reusing primary antibodies is generally not suggested, as it can result in variable findings. Fresh antibody dilutions improve dependability.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "DSG2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3317z | Mouse Anti-DSG2 Recombinant Antibody (clone 19F5) | WB, IP, IF | Mouse IgG1, κ |
| MRO-0474-CN | Rabbit Anti-DSG2 Recombinant Antibody (clone JB96-37) | WB, IHC, FC | Rabbit IgG |
| HPAB-N0063-YC | Mouse Anti-DSG2 Recombinant Antibody (HPAB-N0063-YC) | FC, WB | Mouse IgG |
| VS1-YJ45 | Mouse Anti-DSG2 Recombinant Antibody (clone 10D2) | IB, IF, IP | Mouse IgG1 |
| VS1-YJ46 | Mouse Anti-DSG2 Recombinant Antibody (clone 7H9) | WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1054 | Hi-Affi™ Rabbit Anti-DSG2 Recombinant Antibody (clone DS1054AB) | WB, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0063-YC-S(P) | Mouse Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-N0063-YC-S(P)) | FC, WB | Mouse scFv |
| HPAB-N0064-YC-S(P) | Mouse Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-N0064-YC-S(P)) | FC, WB | Mouse scFv |
| HPAB-0405-FY-S(P) | Human Anti-DSG2 Recombinant Antibody; scFv Fragment (HPAB-0405-FY-S(P)) | FC, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0063-YC-F(E) | Mouse Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-N0063-YC-F(E)) | FC, WB | Mouse Fab |
| HPAB-N0064-YC-F(E) | Mouse Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-N0064-YC-F(E)) | FC, WB | Mouse Fab |
| HPAB-0405-FY-F(E) | Human Anti-DSG2 Recombinant Antibody; Fab Fragment (HPAB-0405-FY-F(E)) | FC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY80 | AbPlus™ Anti-DSG2 Magnetic Beads (10D2) | IP, Protein Purification | |
| VS-0724-YC1365 | AbPlus™ Anti-DSG2 Magnetic Beads (VS-0724-YC1365) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY101 | CytoStream™ Mouse Anti-DSG2 Recombinant Antibody (clone 6D8) | FC | Mouse IgG1, kappa |
| VS13-YC325 | CytoStream™ Rabbit Anti-DSG2 Recombinant Antibody (VS13-YC325) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY699 | Anti-DSG2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2094 | Anti-Human DSG2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY21 | Human Anti-DSG2 scFv-Fc Chimera (VS-0425-FY21) | FC, IP | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC466 | Recombinant Anti-DSG2 Vesicular Antibody, EV Displayed (VS-0425-YC466) | ELISA, FC, Cell-uptake |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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