This is a human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. The clone (D3)1b/3a derived from libraries panned on Dsg3 which binds Dsg3 but not Dsg1.
Figure 1 IF of (D3)1b/3a scFv mAbs on human epidermis.
The ScFv mAb used as primary antibody for staining human epidermis is indicated. Magnification, ×400.
Payne, A. S., Ishii, K., Kacir, S., Lin, C., Li, H., Hanakawa, Y., ... & Siegel, D. L. (2005). Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. The Journal of clinical investigation, 115(4), 888-899.
Figure 2 Characterization of scFv mAb desmoglein-binding specificity by ELISA.
Patterns of the binding of selected scFv mAb clones to Dsg1 and Dsg3.
Payne, A. S., Ishii, K., Kacir, S., Lin, C., Li, H., Hanakawa, Y., ... & Siegel, D. L. (2005). Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. The Journal of clinical investigation, 115(4), 888-899.
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CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-172 | Human Anti-DSG3 Recombinant Antibody (clone PVA3) | ELISA | Human IgG |
MOB-2196MZ | Recombinant Mouse Anti-Human DSG3 Antibody (clone 4H244) | ICC/IF, IHC-P, IP, WB | Mouse antibody |
VS3-QX332 | Mouse Anti-DSG3 Recombinant Antibody (clone 1G6A7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
VS3-QX333 | Mouse Anti-DSG3 Recombinant Antibody (clone 11G-2C) | WB, IHC, FC | Mouse IgG1 |
VS4-WK149 | Mouse Anti-DSG3 Recombinant Antibody (clone 4C2) | ELISA | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-258MZ | Anti-Human DSG3 Recombinant Antibody (DF151) | IHC, FC | |
TAB-259MZ | Anti-Human DSG3 Recombinant Antibody (DF364) | IHC, FC | |
TAB-258MZ-S(P) | Anti-Human DSG3 Recombinant Antibody scFv Fragment (DF151) | IHC, FC | |
TAB-259MZ-S(P) | Anti-Human DSG3 Recombinant Antibody scFv Fragment (DF364) | IHC, FC | |
TAB-260MZ-S(P) | Anti-Human DSG3 Recombinant Antibody scFv Fragment (DF366) | IHC, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1055 | Hi-Affi™ Rabbit Anti-DSG3 Recombinant Antibody (clone DS1055AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0203-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3)1b/3a); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0204-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3);3c/9); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0205-CN-S(P) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3a/9); scFv Fragment | ELISA, IF, IB | Human scFv |
FAMAB-0152JF-S(P) | Human Anti-DSG3 Recombinant Antibody (clone PVMAB786); scFv Fragment | IF, WB, ELISA, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0203-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)1b/3a); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0204-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3c/9); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0205-CN-F(E) | Human Anti-DSG3 Recombinant Antibody (clone (D3)3a/9); Fab Fragment | ELISA, IF, IB | Human Fab |
FAMAB-0152JF-F(E) | Human Anti-DSG3 Recombinant Antibody (clone PVMAB786); Fab Fragment | IF, WB, ELISA, FuncS | Human Fab |
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