Human Anti-DSG3 Recombinant Antibody (clone PVMAB786); scFv Fragment (CAT#: FAMAB-0152JF-S(P))
Recombinant monoclonal antibody specially binds to desmoglein 3 (Dsg3). This human anti-Dsg3 antibody PVMAB786 can e a useful reagent to study the mechanism of cell adhesion and detachment on tumor biology, specifically squamous cell carcinomas.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Esophagus
(Squamous epithelial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56863/148897_B_5_1.jpg
(Squamous epithelial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56863/148897_B_5_1.jpg
Figure 2 RNA cell line category: Group enriched (HaCaT, hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134757-DSG3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000134757-DSG3
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human Dsg3
- Species Reactivity
- Human
- Clone
- PVMAB786
- Applications
- IF, WB, ELISA, FuncS
- Related Disease
- Pemphigus vulgaris
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Desmoglein 3; 130 KDa Pemphigus Vulgaris Antigen; Cadherin Family Member 6; CDHF6; PVA; Desmoglein 3 (Pemphigus Vulgaris Antigen); Pemphigus Vulgaris Antigen
- Gene ID
- 1830
- UniProt ID
- P32926
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-172 | Human Anti-DSG3 Recombinant Antibody (clone PVA3) | ELISA | Human IgG |
| VS3-QX332 | Mouse Anti-DSG3 Recombinant Antibody (clone 1G6A7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-QX333 | Mouse Anti-DSG3 Recombinant Antibody (clone 11G-2C) | WB, IHC, FC | Mouse IgG1 |
| VS4-WK149 | Mouse Anti-DSG3 Recombinant Antibody (clone 4C2) | ELISA | Mouse IgG1 |
| VS11-QX61 | Mouse Anti-DSG3 Recombinant Antibody (clone AK23) | ELISA, IF, IP | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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