Recombinant Human Anti-E2 protein Antibody (E8) (CAT#: HPAB-J0064-YC)
Provided is a human monoclonal antibody capable of recognizing the conformational epitope of the HCV E2 glycoprotein and cross-reacting with a plurality of different HCV genotypes, as a medicament for the treatment or prevention of HCV infections.
Specific Inquiry
Neut
Figure 1 The neutralization activity of the e8 Fab using virus pseudoparticles bearing E1E2 from genotype Ia (UKN1A20.8).
Data obtained from different concentrations of immunoaffϊnitypurified e8 and c333 Fabs (negative control) is shown. The experiment was performed three times and the means and standard errors are reported.
FC
Figure 2 The binding of the e8 Fab (lOug/ml) to cells infected with HCV E1-E2 pp of genotype 1 a by indirect flow cytometry.
The e8 Fab binds to a significant proportion of HCV E1E2 pp Ia infected cells. The binding is specific and significantly higher than binding of e8 to uninfected cells, as demonstrated on the horizontal scale, measuring log fluorescence intensity, where a significant proportion of HCV E1E2 pp Ia infected cells show a high level of fluorescence compared to uninfected cells.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- HCV
- Species Reactivity
- HCV
- Clone
- E8
- Applications
- Neut, FC
Product Property
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles
Applications
- Application Notes
- This antibody has been reported for use in Neutralization and Flow Cytometry.
Target
- Alternative Names
- HCV E2 protein
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone E8"
See other products for "E2 Protein"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0060-YC | Recombinant Human Anti-E2 Protein Antibody (TRN1001) | ELISA, FC, Neut | Human IgG |
| HPAB-M0061-YC | Recombinant Human Anti-E2 Protein Antibody (TRN1002) | ELISA, FC, Neut | Human IgG |
| HPAB-M0347-YC | Recombinant Mouse Anti-E2 Protein Antibody (15A9) | ELISA, Neut | Mouse IgG2b, κ |
| HPAB-AP062-YC | Recombinant Mouse Anti-E2 Protein Antibody (MAb II) | ELISA, FC, Neut | |
| HPAB-AP063-YC | Recombinant Mouse Anti-E2 Protein Antibody (MAb VI) | ELISA, FC, Neut |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0060-YC-S(P) | Recombinant Human Anti-E2 Protein Antibody scFv Fragment (TRN1001) | ELISA, FC, Neut | Human scFv |
| HPAB-M0061-YC-S(P) | Recombinant Human Anti-E2 Protein Antibody scFv Fragment (TRN1002) | ELISA, FC, Neut | Human scFv |
| HPAB-M0062-YC-S(P) | Human Anti-E2 Protein Recombinant Antibody; scFv Fragment (HPAB-M0062-YC-S(P)) | ELISA, FC, Neut | Human scFv |
| HPAB-AP062-YC-S(P) | Recombinant Mouse Anti-E2 Protein Antibody scFv Fragment (MAb II) | ELISA, FC, Neut | |
| HPAB-J0064-YC-S(P) | Recombinant Human Anti-E2 protein Antibody scFv Fragment (E8) | ELISA, IF (10 µg/mL), FC (10 µg/mL), Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0060-YC-F(E) | Recombinant Human Anti-E2 Protein Antibody Fab Fragment (TRN1001) | ELISA, FC, Neut | Human Fab |
| HPAB-M0061-YC-F(E) | Recombinant Human Anti-E2 Protein Antibody Fab Fragment (TRN1002) | ELISA, FC, Neut | Human Fab |
| HPAB-M0062-YC-F(E) | Human Anti-E2 Protein Recombinant Antibody; Fab Fragment (HPAB-M0062-YC-F(E)) | ELISA, FC, Neut | Human Fab |
| HPAB-AP062-YC-F(E) | Recombinant Mouse Anti-E2 Protein Antibody Fab Fragment (MAb II) | ELISA, FC, Neut | |
| HPAB-AP063-YC-F(E) | Recombinant Mouse Anti-E2 Protein Antibody Fab Fragment (MAb VI) | ELISA, FC, Neut |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-J0064-YC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.