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Recombinant Anti-EGFR Antibody (F4) (FAMAB-0094YC)

Provided is a internalizing antibody directed against EGFR (epidermal growth factor receptor), a tyrosine kinase receptor that is overexpressed in a wide range of tumour cells. The clone F4 bound native EGFR-bearing cell lines and could be internalized, but did not bind EGFR-negative cell lines. F4 could be used to target therapeutic agents into tumour cells and was expected to be nonimmunogenic in humans.      

  • Datasheet

Specifications
Host
Human
Derivation
Phage display library
Type
Human IgG
Specificity
Human EGFR
Species Reactivity
Human
Clone
F4
Applications
ELISA, Western Blot, Flow Cytometry
Related Disease
Tumor
Target
Alternative Names
ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Entrez Gene ID
1956
UniProt ID
Q504U8

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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Increase Efficiency to Accelerate Your Research & 
Discovery Process

Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. Our service portfolio includes mouse and rat monoclonal antibody production ...

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