Mouse Anti-EGFR Recombinant Antibody (VS3-FY2695)
CAT#: VS3-FY2695
The anti-EGFR antibody is specifically created to bind human EGFR protein. It exhibits cross-reactivity with monkey. This monoclonal antibody proves valuable in disease research related to cancer.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg
Normal Tissue
Figure 3 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg
Normal Tissue
Figure 7 Placenta
Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg
Normal Tissue
Figure 8 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enriched (A-431)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR
❮
❯
| Sub Cat | Host Animal | Species Reactivity | Application | Application Notes | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS3-FY2781 | Mouse | Human, Monkey | WB, ICC, IP |
Immunoprecipitation: 1/20 Western Blot: 1/500-1/1000 Immunocytochemistry: 1/50-1/200 |
||||||
| VS3-FY2696 | Rabbit | Human, Mouse | WB, IHC, ICC, IP |
Immunoprecipitation: 1/20 Western Blot: 1/500-1/1000 Immunohistochemistry: 1/50-1/100 Immunocytochemistry: 1/50-1/200 |
Specifications
- Type
- Mouse IgG
- Specificity
- Epidermal growth factor receptor of human and monkey origins
- Conjugate
- Unconjugated, FITC
- Related Disease
- Cancer
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Epidermal Growth Factor Receptor; Receptor Tyrosine-Protein Kinase ErbB-1; Erb-B2 Receptor Tyrosine Kinase 1; Proto-Oncogene C-ErbB-1; EC 2.7.10.1; ERBB1; ERBB; HER1; Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian)
- Gene ID
- 1956
- UniProt ID
- P00533
- Cellular Localization
- Cell membrane, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Nucleus, Secreted
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Related Diseases
Bladder Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Hepatocellular Carcinoma
Cushing Syndrome
Related Signaling Pathways
JAK-STAT Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H35 | Anti-Human EGFR Recombinant Antibody (Futuximab) | IF, WB, Inhib | IgG1 - kappa |
| TAB-003 | Anti-Human EGFR Recombinant Antibody (Cetuximab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| TAB-302MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-302MZ-S(P)) | ELISA | Mouse scFv |
| TAB-308MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-308MZ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-272MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-272MZ-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-080 | Human Anti-EGFR Recombinant Antibody (PABL-080) | ELISA, WB, FuncS | Human IgG |
| HPAB-0161CQ | Human Anti-EGFR Recombinant Antibody (HPAB-0161CQ) | ELISA, FC, IHC | Human IgG1 |
| HPAB-0060-WJ | Human Anti-EGFR Recombinant Antibody (HPAB-0060-WJ) | ELISA, RIA, FC | Human IgG1, κ |
| HPAB-0661LY | Human Anti-EGFR Recombinant Antibody (HPAB-0661LY) | ELISA | Human IgG |
| HPAB-0136-YJ | Human Anti-EGFR Recombinant Antibody (HPAB-0136-YJ) | ELISA, FC, Inhib, FuncS | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-274MZ | Human Anti-EGFR Recombinant Antibody (TAB-274MZ) | FC | Humanized IgG |
| TAB-274MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-274MZ-F(E)) | FC | Humanized Fab |
| TAB-297MZ-F(E) | Anti-Human EGFR Recombinant Antibody Fab Fragment (H225) | ELISA, WB | Humanized antibody |
| TAB-298MZ-F(E) | Anti-Human EGFR Recombinant Antibody Fab Fragment (Hu225) | ELISA, WB | Humanized antibody |
| PABX-052 | Recombinant Human Anti-EGFR Antibody (PABX-052) | WB, ELISA, FuncS, IB, FC, SPR, Apop | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-301MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-301MZ-S(P)) | ELISA | Mouse scFv |
| TAB-303MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-303MZ-S(P)) | ELISA | Mouse scFv |
| TAB-304MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-304MZ-S(P)) | ELISA | Mouse scFv |
| TAB-305MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-305MZ-S(P)) | ELISA | Mouse scFv |
| TAB-306MZ-S(P) | Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-306MZ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-278MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-278MZ-F(E)) | ELISA, WB | Human Fab |
| TAB-279MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-279MZ-F(E)) | ELISA, WB | Human Fab |
| TAB-282MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-282MZ-F(E)) | ELISA | Human Fab |
| TAB-283MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-283MZ-F(E)) | ELISA | Human Fab |
| TAB-284MZ-F(E) | Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-284MZ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-055LC | Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Chimeric antibody (mouse/human) |
| Gly-144LC | Recombinant Anti-Human EGFR Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-055LC-1 | Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-167LC | Recombinant Anti-Human EGFR Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0183MZ | Chicken Anti-EGFR Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC773 | A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer | FCM | |
| MHC-LC4545 | PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer | FCM | |
| MHC-YF409 | A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-722CQ | Rabbit Anti-EGFR Recombinant Antibody (clone CBL1011) | Neut | Rabbit IgG |
| NEUT-723CQ | Mouse Anti-EGFR Recombinant Antibody (clone CBL931) | WB, IP, IHC, ICC, Neut | Mouse IgG1 |
| NEUT-724CQ | Rabbit Anti-EGFR Recombinant Antibody (NEUT-724CQ) | IF, FC, WB, IP, Neut | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1101 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone DS1101AB) | IHC-P | Rabbit IgG |
| MOR-4520 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH28DS) | IF, ICC, FC | Rabbit IgG |
| MOR-4570 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH82DS) | ELISA | Rabbit IgG |
| MOR-4571 | Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH83DS) | WB, IF, ICC, FC | Rabbit IgG |
| MOR-0033-FY | Rabbit Anti-EGFR Recombinant Antibody (clone AFY0004) | ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0094-YC-S(P) | Human Anti-EGFR Recombinant Antibody (clone F4); scFv Fragment | ELISA, WB, FC | Human scFv |
| HPAB-0044-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone TGM10-1); scFv Fragment | FC | Humanized scFv |
| HPAB-0089-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone MIL27-3); scFv Fragment | FC | Humanized scFv |
| HPAB-0119-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone huML66); scFv Fragment | Inhib | Humanized scFv |
| HPAB-0122-FY-S(P) | Mouse Anti-EGFR Recombinant Antibody (clone L2-H3); scFv Fragment | ELISA, WB | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0202-CN-F(E) | Human Anti-EGFR Recombinant Antibody (clone E10); Fab Fragment | ELISA, WB | Human Fab |
| HPAB-1122-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone P2/1); Fab Fragment | FC | Human Fab |
| HPAB-1123-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone P2/2); Fab Fragment | FC | Human Fab |
| HPAB-1124-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone P2/4); Fab Fragment | FC | Human Fab |
| HPAB-1125-FY-S(P) | Human Anti-EGFR Recombinant Antibody (clone 2224); Fab Fragment | FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-165 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-165) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-464CQ | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-464CQ) | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-003 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-003) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-040 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-040) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-119 | Afuco™ Anti-EGFR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-119) | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP881-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP881-YC) | ELISA, FC, IP, FuncS | Llama VHH |
| HPAB-AP882-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP882-YC) | ELISA | Llama VHH |
| HPAB-AP883-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP883-YC) | ELISA | Llama VHH |
| HPAB-AP884-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP884-YC) | ELISA | Llama VHH |
| HPAB-AP885-YC | Recombinant Llama Anti-EGFR Single Domain Antibody (HPAB-AP885-YC) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY84 | AbPlus™ Anti-EGFR Magnetic Beads (pSEX81-6) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC32 | Mouse Anti-EGFR Recombinant Antibody (VS-0924-YC32) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC35 | Rabbit Anti-EGFR Antibody (VS-0924-YC35) - Cancer Stem Cell Marker | IHC, WB, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY177 | Mouse Anti-NHP EGFR Recombinant Antibody (clone 225) | IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY28 | Human Anti-EGFR (clone ABT-806) scFv-Fc Chimera | FC, Cyt | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY102 | CytoStream™ Mouse Anti-EGFR Recombinant Antibody (VS-0225-XY102) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY735 | Anti-EGFR Immunohistochemistry Kit | IHC | |
| VS-0525-XY2183 | Anti-Mouse EGFR Immunohistochemistry Kit | IHC | |
| VS-0525-XY2182 | Anti-Human EGFR Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC340 | Recombinant Anti-EGFR Vesicular Antibody, EV Displayed (VS-0425-YC340) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC65 | Recombinant Anti-EGFR (AA 269-278 x AA 526-535) Biparatopic Antibody, Tandem scFv (Clone Pep 2 x Clone Pep 3) | FC | Tandem scFv |
| VS-0525-YC66 | Recombinant Anti-EGFR (AA 582-591 x AA 606-614) Biparatopic Antibody, Tandem scFv (Clone Pep 4 x Clone Pep 1) | FC | Tandem scFv |
| VS-0525-YC68 | Recombinant Anti-EGFR (AA 526-535 x AA 600-605) Biparatopic Antibody, Tandem scFv (Clone Pep 3 x Clone Pep 5) | FC | Tandem scFv |
| VS-0525-YC213 | Recombinant Anti-EGFR (Domain II x Domain III) Biparatopic Antibody, Tandem scFv | ELISA, FC, IF, IHC, IP | Tandem scFv |
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