Rabbit Anti-Borrelia burgdorferi OspB Antibody (VS-0925-XY6)
CAT#: VS-0925-XY6
Borrelia burgdorferi OspB antibodies target this adhesion protein, enabling ELISA for detection, immunofluorescence on bacterial surfaces, and neutralization assays to research its role in host colonization during early infection.
Specifications
- Host Animal
- Rabbit
- Applications
- WB, ELISA, IP
- Specificity
- Borrelia burgdorferi OspB
- Target
- Borrelia burgdorferi OspB
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Protein A Purified
- Format
- Lyophilized
- Buffer
- Potassium phosphate, pH 7.2, with 0.15M NaCl
- Preservative
- 0.01% sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Borrelia burgdorferi OspB, or Outer Surface Protein B, belongs to the same outer membrane protein family as OspA, with structural homology and co-expression (especially in ticks). It mediates bacterial adhesion to tick intestinal epithelial cells, assisting OspA in enhancing colonization. In the early host infection stage, it may also participate in bacterial-host cell interactions to support early colonization. Unlike OspA, it may maintain expression in the late infection stage, becoming an immune target. OspB is a potential candidate antigen for Lyme disease vaccines, and combined use with OspA may expand protection range and improve preventive effects.
- Alternative Names
- B. burgdorferi Outer Surface Protein B, Bb OspB
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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