Rabbit Anti-Mycobacterium tuberculosis Tb10.4 Antibody (VS-0925-XY47)
CAT#: VS-0925-XY47
Mycobacterium tuberculosis Tb10.4 antibodies bind this RD1-linked protein, supporting Western blotting, flow cytometry for surface expression, and studies on its role in membrane disruption. Critical for dissecting Tb10.4's contributions to tuberculosis infection progression.
Specifications
- Host Animal
- Rabbit
- Applications
- WB, ELISA
- Specificity
- Mycobacterium tuberculosis Tb10.4
- Target
- Mycobacterium tuberculosis Tb10.4
- Immunogen
- Recombinant Tb10.4 protein
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Affinity chromatography Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- 15 mM sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Mycobacterium tuberculosis Tb10.4 is another small protein of Mycobacterium tuberculosis, closely related to Tb10.3 and also encoded in the RD1 locus. It shares structural similarities with Tb10.3 but may have distinct functional roles. Preliminary research indicates Tb10.4 may be involved in bacterial virulence, possibly contributing to host cell membrane disruption or modulation of host immune responses to facilitate bacterial survival. It has immunogenicity, capable of triggering T-cell responses in the host, especially in individuals with latent or active tuberculosis. This makes Tb10.4 a potential candidate for tuberculosis vaccines, as it can target key virulence-associated pathways. Additionally, it may serve as a complementary diagnostic marker, aiding in the detection of infections, particularly in cases where other markers (e.g., ESAT-6) may be less sensitive.
- Alternative Names
- M. tuberculosis Tuberculosis Protein 10.4, Mtb Tb10.4
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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