Rabbit Anti-Staphylococcus aureus LDHA Antibody (VS-0925-XY60)
CAT#: VS-0925-XY60
Staphylococcus aureus LDHA antibodies recognize this lactate dehydrogenase, enabling Western blotting under hypoxic conditions, ELISA for detection, and studies on its role in anaerobic glycolysis. Valuable for researching Staphylococcus aureus survival in abscesses or deep tissues.
Specifications
- Host Animal
- Rabbit
- Applications
- WB
- Specificity
- Staphylococcus aureus LDHA
- Target
- Staphylococcus aureus LDHA
- Species Reactivity
- Bacteria
- Type
- Rabbit IgG
- Purification
- Protein G Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.4, with 50% glycerol
- Preservative
- 0.03% ProClin 300
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Staphylococcus aureus LDHA (Lactate Dehydrogenase A) is a metabolic enzyme of Staphylococcus aureus, a Gram-positive bacterium responsible for diverse infections. LDHA catalyzes the final step of anaerobic glycolysis, converting pyruvate to lactate while regenerating NAD+-a coenzyme essential for sustaining glycolysis. This function is critical for Staphylococcus aureus survival, especially in oxygen-limited (hypoxic) host environments like abscesses or deep tissue infections, where aerobic respiration is impaired. By maintaining glycolytic flux, LDHA ensures the bacterium produces sufficient energy (ATP) to grow and replicate. Beyond metabolism, LDHA may also contribute to bacterial virulence by regulating the production of other virulence factors or modifying the host's local microenvironment (e.g., acidifying tissues via lactate production, which can inhibit immune cell function). Due to its role in essential anaerobic metabolism, LDHA is a potential target for anti-staphylococcal drugs; inhibiting LDHA could disrupt energy production and limit bacterial survival in hypoxic infection sites.
- Alternative Names
- S. aureus Lactate Dehydrogenase A, Sa LDHA
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0925-XY60. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, Inhib, IP, ELISA
Application: SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
-4.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
Application: ELISA, Activ, Block
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
