Mouse Anti-Treponema pallidum p47 Antibody (VS-0925-XY76)
CAT#: VS-0925-XY76
Treponema pallidum p47 antibodies (duplicate) enable studies on p47's role in chronic syphilis and support development of p47-targeted vaccines. Reliable for translational syphilis research.
Specifications
- Host Animal
- Mouse
- Applications
- WB, ICC, IF, ELISA
- Specificity
- Treponema pallidum p47
- Target
- Treponema pallidum p47
- Species Reactivity
- Bacteria
- Type
- Mouse IgG2b
- Purification
- Protein A Purified
- Format
- Liquid
- Buffer
- PBS, pH 7.2
- Preservative
- 0.1% sodium azide
- Storage
- This item should be kept at 4°C if stored for a short period (1 to 2 weeks). For extended storage, maintain a temperature of -20°C. Repeated freeze-thaw cycles must be avoided.
Target
- Introduction
- Treponema pallidum p47 is a major outer membrane protein of Treponema pallidum, the pathogen responsible for syphilis. Its primary biological function is to mediate the bacterium's adhesion to host cells, which is critical for establishing infection after transmission (e.g., via sexual contact). Without this adhesion, Treponema pallidum cannot attach to mucosal tissues and would be cleared by the host's natural defenses. P47 is also one of the most immunogenic proteins of Treponema pallidum, meaning it triggers a strong antibody response in infected people. These antibodies are used in diagnostic tests to identify syphilis, as they are present in all stages of the disease (except very early primary syphilis). Due to its role in adhesion and its immunogenicity, p47 is a key target for syphilis vaccine development. A vaccine that induces anti-p47 antibodies could prevent Treponema pallidum from adhering to host cells, stopping infection before it progresses to symptoms. This makes p47 a vital molecule for both syphilis diagnosis and prevention efforts.
- Alternative Names
- T. pallidum Major Outer Membrane Protein p47, Tp p47 Antigen
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "Treponema pallidum p47"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0925-XY72 | Mouse Anti-Treponema pallidum p47 Antibody (VS-0925-XY72) | WB, ICC, IF, ELISA | Mouse IgG2a |
| VS-0925-XY73 | Mouse Anti-Treponema pallidum p47 Antibody (VS-0925-XY73) | WB, ICC, IF, ELISA | Mouse IgG2b |
| VS-0925-XY74 | Mouse Anti-Treponema pallidum p47 Antibody (VS-0925-XY74) | WB, ICC, IF, ELISA | Mouse IgG2b |
| VS-0925-XY75 | Mouse Anti-Treponema pallidum p47 Antibody (VS-0925-XY75) | WB, ICC, IF, ELISA | Mouse IgG2b |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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