Afuco™ Anti-ENG ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-013ML)

CAT#: AFC-TAB-013ML

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ENG. It is a human monoclonal antibody.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IHC staining of human placenta Figure 3 IF staining of human cell line BJ Figure 4 IF staining of human cell line SiHa Figure 5 Kidney Figure 6 RNA cell line category: Cell line enhanced (fHDF/TERT166, HUVEC TERT2, TIME)

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Chimeric
  • Type
  • ADCC enhanced antibody
  • Specificity
  • Human ENG
  • Species Reactivity
  • Human
  • Applications
  • ELISA, IHC, FC, IP, IF, Inhib
  • Conjugate
  • Unconjugated
  • Generic Name
  • Carotuximab
  • Related Disease
  • Hepatocellular Carcinoma, Gestational Trophoblastic Neoplasia, Choriocarcinoma, Placental Site Trophoblastic Tumor, Epithelioid Trophoblastic Tumor, Adult Solid Tumor, Advanced Soft Tissue Sarcoma, Metastatic Breast Cancer, Solid Tumors, Lung Cancer, Hepatoma, Liver Neoplasms, AdenomaLiver Cell, Carcinoma Hepatocellular, Liver Neoplasms Experimental, Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Giant Cell Glioblastoma, Adult Gliosarcoma, Adult Mixed Glioma, Recurrent Adult Brain Neoplasm, Choriocarcinoma

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Endoglin; ORW; ORW1; Osler-Rendu-Weber syndrome 1; CD105; END; HHT1
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Biosimilar Overview

Please refer to Carotuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Carotuximab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "Carotuximab"

DrugMonitor™ Anti-Carotuximab Antibody (VS-1224-YC256)
Carotuximab (TRC105) is a human/murine chimeric monoclonal antibody against endoglin (CD105) with potential antiangiogenic and antineoplastic effects, used for cancer treatment. The DrugMonitor™ Anti-Carotuximab Antibody (VS-1224-YC256) is an anti-drug antibody (ADA) against Carotuximab. This drug-based antibody is raised in mice immunized with the Carotuximab. The anti-Carotuximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Carotuximab in samples.

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