Human Anti-EPCAM Recombinant Antibody (clone 3-17I)
CAT#: VS11-QX62
This product is a recombinant human antibody that recognizes EPCAM. This antibody has an affinity for human EpCAM and also exhibits cross-reactivity with Cynomolgus monkey EpCAM. This antibody can be used for the following applications: FC, IHC, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg
Normal Tissue
Figure 2 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Human IgG1, κ
- Specificity
- Human and Cynomolgus monkey EpCAM
- Species Reactivity
- Human, Cynomolgus monkey
- Clone
- 3-17I
- Applications
- FC, IHC, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
- Gene ID
- 4072
- UniProt ID
- P16422
- Long Name
- Epithelial cell adhesion molecule
- Sequence Similarities
- Belongs to the EPCAM family.
- Cellular Localization
- Plasma membrane
- Function
- May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "EPCAM"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-112-F(E) | Anti-Human EpCAM Recombinant Antibody Fab Fragment, 17-1A (Citatuzumab Bogatox) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Fab - G1 - kappa |
| TAB-362MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
| TAB-374MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8B) | FC, ELISA | Humanized antibody |
| TAB-375MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h12H8C) | FC, ELISA | Humanized antibody |
| TAB-376MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (h2D11B) | FC, ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0531CL-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (HE2) | ELISA, Inhib | |
| TAB-363MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-363MZ) | ELISA, FuncS | Mouse IgG1, κ |
| TAB-364MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-364MZ) | FC | Mouse IgG1 |
| TAB-365MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-365MZ) | FC | Mouse IgG1 |
| TAB-366MZ | Mouse Anti-EPCAM Recombinant Antibody (TAB-366MZ) | ELISA, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-356MZ | Anti-Human EPCAM Recombinant Antibody (3-171) | Cyt, ELISA, FC, WB | Human antibody |
| TAB-357MZ | Anti-Human EPCAM Recombinant Antibody (7-F17) | ELISA | Human antibody |
| TAB-358MZ | Anti-Human EPCAM Recombinant Antibody (12-C15) | ELISA | Human antibody |
| TAB-359MZ | Anti-Human EPCAM Recombinant Antibody (16-G5) | ELISA | Human antibody |
| TAB-360MZ | Anti-Human EPCAM Recombinant Antibody (17-C20) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0538-CN | Mouse Anti-EPCAM Recombinant Antibody (clone 3-E1-E2) | WB, IF, IHC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-106) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-213) | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
| AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-701) | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
| HPAB-2217LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) | ELISA | Human Fab |
| HPAB-2218LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) | ELISA | Human Fab |
| HPAB-2219LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) | ELISA | Human Fab |
| HPAB-2220LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2218LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2218LY-S(P)) | ELISA | Human scFv |
| HPAB-2219LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2219LY-S(P)) | ELISA | Human scFv |
| HPAB-2220LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2220LY-S(P)) | ELISA | Human scFv |
| HPAB-2221LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2221LY-S(P)) | ELISA | Human scFv |
| HPAB-2222LY-S(P) | Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2222LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
| MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1316WJ | Human Anti-EPCAM Recombinant Antibody (clone LD9) | ELISA | Humanized IgG |
| ZG-0014C | Mouse Anti-EPCAM Recombinant Antibody (clone ABT-EPCAM) | IHC-P, IF, ICC | Mouse IgG |
| ZG-0652J | Rabbit Anti-EPCAM Recombinant Antibody (clone 3H12) | ELISA, WB | Rabbit IgG |
| ZG-0653J | Rabbit Anti-EPCAM Recombinant Antibody (clone 6H12) | ELISA, WB, IHC | Rabbit IgG |
| VS-0224-XY43 | Human Anti-EpCAM Recombinant Antibody (VS-0224-XY43) | ELISA, FC | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1517 | AbPlus™ Anti-EPCAM Magnetic Beads (VS-0724-YC1517) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC37 | Mouse Anti-EPCAM Recombinant Antibody (VS-0924-YC37) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC38 | Rabbit Anti-EPCAM Antibody (VS-0924-YC38) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY18 | Human Anti-EpCAM (clone 3-171) scFv-Fc Chimera | Cyt, ELISA, FC, WB | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY107 | CytoStream™ Mouse Anti-EPCAM Recombinant Antibody (VS-0225-XY107) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY773 | Anti-EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2307 | Anti-Human EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2308 | Anti-Mouse EPCAM Immunohistochemistry Kit | IHC | |
| VS-0525-XY2309 | Anti-Canine EPCAM Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC210 | Recombinant Anti-EPCAM Vesicular Antibody, EV Displayed (VS-0425-YC210) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC214 | Recombinant Anti-EpCAM (Exon 2 x Exon 5) Biparatopic Antibody, Tandem scFv (Edrecolomab x Adecatumumab) | ELISA, FC | Tandem scFv |
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