Human Anti-EPCAM Recombinant Antibody (clone ch FU-MK-1)

Name: Human Anti-EPCAM Recombinant Antibody (clone ch FU-MK-1)
SKU: HPAB-0639-YJ
Rating: 5 (1 reviews)

CAT#: HPAB-0639-YJ

This product is a recombinant chimeric (mouse/human) antibody that recognizes human EPCAM. Ch FU-MK-1 also showed a potent antibody-dependent cell-mediated cytotoxicity (ADCC) with human peripheral blood mononuclear cells as effectors against the adenocarcinoma cells, indicating that this chimeric antibody seems to be suitable for in vivo therapeutic approaches.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg

Normal Tissue Figure 2 Thyroid gland

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg

Normal Tissue Figure 3 Colon

Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM

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Specifications

Host Species
Human

Type
Chimeric (mouse/human) IgG1, κ

Specificity
Human EPCAM

Species Reactivity
Human

Clone
ch FU-MK-1

Applications
ELISA, FC, WB, ADCC

Related Disease
Gastric adenocarcinoma

Product Property

Purification
Protein A/G purified

Buffer
PBS

Preservative
No preservatives

Storage
Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.

Target

Alternative Names
Tumor-associated antigen GA733-2; GA733-2; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial cell adhesion molecule; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1

Gene ID
4072

UniProt ID
P16422

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0639-YJ.pdf

MSDS

MSDS - HPAB-0639-YJ.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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CAT
Product Name

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HPAB-2218LY-F(E)	Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E))	ELISA	Human Fab
HPAB-2219LY-F(E)	Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E))	ELISA	Human Fab
HPAB-2220LY-F(E)	Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
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HPAB-2220LY-S(P)	Human Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-2220LY-S(P))	ELISA	Human scFv
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CAT	Product Name	Application	Type
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