AbPlus™ Anti-EPHB3 Magnetic Beads (VS-0424-XY88) (CAT#: VS-0424-XY88)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-EPHB3 specific antibody

• Target
• EPHB3

• Immunogen
• Recombinant form of human EPHB3 extracellular domain (aa 37-558)

• Target Species
• Human

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members.

• Alternative Names
• EPH Receptor B3; Tyrosine-Protein Kinase TYRO6; EPH-Like Tyrosine Kinase 2; Embryonic Kinase 2; EPH-Like Kinase 2; EC 2.7.10.1; TYRO6; ETK2; HEK2; EK2; EPH-Like Tyrosine Kinase-2; Human Embryo Kinase 2; EC 2.7.10; EphB3

• Gene ID
• 2049

• UniProt ID
• P54753

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