Afuco™ Anti-ERBB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-053) (CAT#: AFC-TAB-053)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ERBB2. It is a monoclonal antibody. The first of its class in a line of agents called "HER dimerization inhibitors". By binding to HER2, it inhibits the dimerization of HER2 with other HER receptors, which is hypothesized to result in slowed tumor growth.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Anti-Human ERBB2 Recombinant Antibody (AFC-TAB-053) in SDS-PAGE
SDS-PAGE analysis of AFC-TAB-053 in β-mercaptoethanol-reduced (Lane left) and non-reduced (Lane right) conditions.
ELISA
Figure 2 Anti-Human ERBB2 Recombinant Antibody (AFC-TAB-053) in ELISA
ELISA analysis of AFC-TAB-053 was performed by coating with human ERBB2 protein (His tag).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Trade name
- Pertuzumab, Omnitarg
- Generic Name
- Pertuzumab
- Related Disease
- Prostate cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ERBB2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian);
- Gene ID
- 2064
- UniProt ID
- P04626
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Pertuzumab"
DrugMonitor™ Anti-Pertuzumab Antibody (VS-1224-YC920)Pertuzumab is an antineoplastic agent used in combination with other treatments for HER2-positive metastatic breast cancer. The DrugMonitor™ Anti-Pertuzumab Antibody (VS-1224-YC920) is an anti-drug antibody (ADA) against Pertuzumab. This drug-based antibody is raised in mice immunized with the Pertuzumab. The anti-Pertuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Pertuzumab in samples.
See other products for "ERBB2"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B008(A) | Recombinant Anti-human ERBB2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B008(G) | Recombinant Anti-human ERBB2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B008(T) | Recombinant Anti-human ERBB2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
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