Human Anti-ERBB2 Recombinant Antibody (clone 3.F2) (CAT#: HPAB-1333WJ)
This product is a human antibody which specifically binds to HER2/neu. This antibody can be used for the diagnosis and treatment of HER2/neu-related disease.
Specific Inquiry
IP
Figure 1 Specificity of antibodies against native Her2/neu.
Antibodies from sera of ECD/Her2-immunised mice are specific against the human Her2/neu molecule, as seen with immunoprecipitation assay.
Dimitriadis, A., Gontinou, C., Baxevanis, C. N., & Mamalaki, A. (2009). The mannosylated extracellular domain of Her2/neu produced in P. pastorisinduces protective antitumor immunity. BMc cancer , 9 (1), 386.
ELISA
Figure 2 Vaccination with the mannosylated ECD/Her2 expressed in P. pastoris elicits a humoral response.
Anti-ECD/ Her2 antibodies in the sera of mice immunized with ECD/Her2 or PBS, as measured with enzyme-linked immunosorbent assay (ELISA).
Dimitriadis, A., Gontinou, C., Baxevanis, C. N., & Mamalaki, A. (2009). The mannosylated extracellular domain of Her2/neu produced in P. pastorisinduces protective antitumor immunity. BMc cancer , 9 (1), 386.
Specifications
- Immunogen
- Purified or enriched preparation of HER2/neu antigen
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human HER2/neu
- Species Reactivity
- Human
- Clone
- 3.F2
- Applications
- ELISA, IP
- Related Disease
- HER2/neu-related disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HER2/neu antibody has been reported in applications of Immunoprecipitation, Enzyme-linked Immunosorbent Assay.
Target
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-059 | Recombinant Anti-Human ERBB2 VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| PNBL-066 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-066) | SPR | Llama VHH |
| PNBL-067 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-067) | SPR | Llama VHH |
| PNBL-069 | Recombinant Anti-HER2 VHH Single Domain Antibody (PNBL-069) | ELISA | Llama VHH |
| HPAB-0725-YJ-VHH | Camelid Anti-ERBB2 Recombinant Single Domain Antibody (HPAB-0725-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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