Human Anti-ERBB2 Recombinant Antibody (clone 3.F2) (CAT#: HPAB-1333WJ)
This product is a human antibody which specifically binds to HER2/neu. This antibody can be used for the diagnosis and treatment of HER2/neu-related disease.
Specific Inquiry
IP
Figure 1 Specificity of antibodies against native Her2/neu.
Antibodies from sera of ECD/Her2-immunised mice are specific against the human Her2/neu molecule, as seen with immunoprecipitation assay.
Dimitriadis, A., Gontinou, C., Baxevanis, C. N., & Mamalaki, A. (2009). The mannosylated extracellular domain of Her2/neu produced in P. pastorisinduces protective antitumor immunity. BMc cancer , 9 (1), 386.
ELISA
Figure 2 Vaccination with the mannosylated ECD/Her2 expressed in P. pastoris elicits a humoral response.
Anti-ECD/ Her2 antibodies in the sera of mice immunized with ECD/Her2 or PBS, as measured with enzyme-linked immunosorbent assay (ELISA).
Dimitriadis, A., Gontinou, C., Baxevanis, C. N., & Mamalaki, A. (2009). The mannosylated extracellular domain of Her2/neu produced in P. pastorisinduces protective antitumor immunity. BMc cancer , 9 (1), 386.
Specifications
- Immunogen
- Purified or enriched preparation of HER2/neu antigen
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human HER2/neu
- Species Reactivity
- Human
- Clone
- 3.F2
- Applications
- ELISA, IP
- Related Disease
- HER2/neu-related disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HER2/neu antibody has been reported in applications of Immunoprecipitation, Enzyme-linked Immunosorbent Assay.
Target
Related Resources
Bladder Cancer
Non-small Cell Lung Cancer
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 3.F2"
See other products for "ERBB2"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-059 | Recombinant Anti-Human ERBB2 VHH Single Domain Antibody | IHC, FC, CA, FuncS | Llama VHH |
| HPAB-0201-FY | Recombinant llama Anti-ERBB2 Antibody (VHH6) | E | llama VHH |
| HPAB-0202-FY | Recombinant llama Anti-ERBB2 Antibody (VHH1) | E | llama VHH |
| HPAB-0203-FY | Recombinant llama Anti-ERBB2 Antibody | IF | llama VHH |
| HPAB-0725-YJ-VHH | Camelid Anti-ERBB2 Recombinant Single Domain Antibody (SR-87) | ELISA | Camelid VHH |
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B008(A) | Recombinant Anti-human ERBB2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B008(G) | Recombinant Anti-human ERBB2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B008(T) | Recombinant Anti-human ERBB2 Intrabody [Tat] | ICC, Neut, FuncS | scFv-Tat |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-005 | Anti-Human ErbB2 Recombinant Antibody (Trastuzumab) | FC, IP, ELISA, Neut, FuncS, IF, IHC | IgG1 - kappa |
| TAB-033CT | Human Anti-ERBB2 Recombinant Antibody (TAB-033CT) | ELISA, WB | Human IgG1, κ |
| TAB-038CT | Human Anti-ERBB2 Recombinant Antibody (TAB-038CT) | FuncS, FC | Humanized IgG1 |
| TAB-039CT | Anti-Human HER2/neu Recombinant Antibody (h1E11) | WB | Humanized antibody |
| TAB-041CT | Human Anti-ERBB2 Recombinant Antibody (TAB-041CT) | SPR, ELISA, WB | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-761 | Anti-ERBB2 Recombinant Antibody (Margetuximab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-049CT | Anti-Human HER2/neu Recombinant Antibody (ChA21) | IHC, Inhib, WB, Activ, FC | Chimeric antibody (mouse/human) |
| TAB-049CT-S(P) | Anti-Human HER2/neu Recombinant Antibody scFv Fragment (ChA21) | WB | Chimeric antibody (mouse/human) |
| TAB-049CT-F(E) | Anti-Human HER2/neu Recombinant Antibody Fab Fragment (ChA21) | WB | Chimeric antibody (mouse/human) |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G022E | Anti-ERBB2 immunotoxin 4D5 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G022D | Anti-ERBB2 immunotoxin 4D5 (scFv)-DT | Cytotoxicity assay, Function study | |
| AGTO-G022G | Anti-ERBB2 immunotoxin 4D5 (scFv)-Gel | Cytotoxicity assay, Function study | |
| AGTO-G022R | Anti-ERBB2 immunotoxin 4D5 (scFv)-RTA | Cytotoxicity assay, Function study | |
| AGTO-G022S | Anti-ERBB2 immunotoxin 4D5 (scFv)-Sap | Cytotoxicity assay, Function study |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0191CL | Human Anti-ERBB2 Recombinant Antibody (TAB-0191CL) | ELISA, Cyt, Internalization | Human IgG |
| TAB-0192CL | Human Anti-ERBB2 Recombinant Antibody (TAB-0192CL) | ELISA, ADCC, Cyt, Internalization | Human IgG |
| TAB-0193CL | Human Anti-ERBB2 Recombinant Antibody (TAB-0193CL) | ELISA, ADCC, Cyt, Internalization | Human IgG |
| TAB-0194CL | Human Anti-ERBB2 Recombinant Antibody (TAB-0194CL) | ELISA, ADCC, Cyt, Internalization | Human IgG |
| TAB-0191CL-F(E) | Human Anti-ERBB2 Recombinant Antibody; Fab Fragment (TAB-0191CL-F(E)) | ELISA, Cyt, Internalization | Human Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-157 | Human Anti-ERBB2 Recombinant Antibody (clone F0178C1); scFv Fragment | Neut | Human scFv |
| PSBC-158 | Human Anti-ERBB2 Recombinant Antibody (clone Pertuzumab, 2C4); scFv Fragment | IP, Neut | Human scFv |
| FAMAB-0098-YC-F(E) | Mouse Anti-ERBB2 Recombinant Antibody (clone E402); Fab Fragment | Cyt | Mouse Fab |
| FAMAB-0099-YC-F(E) | Human Anti-ERBB2 Recombinant Antibody (clone CH402); Fab Fragment | Cyt | Human Fab |
| HPAB-0010-FY-F(E) | Human Anti-ERBB2 Recombinant Antibody; Fab Fragment (HPAB-0010-FY-F(E)) | ELISA, FC | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-034CT-F(E) | Anti-Human HER2/neu Recombinant Antibody Fab Fragment (pertuzumab ) | WB | |
| TAB-036CT-F(E) | Anti-Human HER2/neu Recombinant Antibody Fab Fragment (6B2) | ELISA, WB | |
| TAB-037CT-F(E) | Anti-Human HER2/neu Recombinant Antibody Fab Fragment (7C2/7F3) | ELISA, WB | |
| TAB-270CQ-S(P) | Mouse Anti-ERBB2 Recombinant Antibody; scFv Fragment (TAB-270CQ-S(P)) | WB, Inhib | Mouse scFv |
| PABX-082-S (P) | Recombinant Human Anti-HER2 Antibody scFv Fragment (Gr6) | WB, ELISA, FuncS | scFv |
Fab Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-024LC | Recombinant Anti-Human ERBB2 Antibody (Fab glycosylation) | ELISA | Mouse antibody |
| Gly-039LC | Recombinant Anti-Human ERBB2 Antibody (Fab glycosylation) | ELISA | Human antibody |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-117LC | Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-118LC | Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) | ELISA | Mouse antibody |
| Gly-145LC | Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) | ELISA | Human antibody |
| Gly-146LC | Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) | ELISA | Human antibody |
| Gly-147LC | Recombinant Anti-Human ERBB2 Antibody (Fc glycosylation) | ELISA | Human antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-177LC | Recombinant Anti-Human ERBB2 Antibody (Non-glycosylated) | ELISA | Humanized antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0195MZ | Chicken Anti-ERBB2 Polyclonal IgY | WB | Chicken antibody |
| BRD-0695MZ | Chicken Anti-ERBB2 Polyclonal IgY | WB | Chicken antibody |
| BRD-0779MZ | Chicken Anti-ErbB2 Polyclonal IgY | ICC, IF, IHC, IP | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-737CQ | Mouse Anti-ERBB2 Recombinant Antibody (clone 7.16.4) | Block, IP, IF, FC | Mouse IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1178 | Hi-Affi™ Rabbit Anti-ERBB2 Recombinant Antibody (clone DS1178AB) | IHC-P, IHC-Fr | Rabbit IgG |
| MOR-4586 | Hi-Affi™ Rabbit Anti-ERBB2 Recombinant Antibody (clone TH99DS) | WB | Rabbit IgG |
| MOR-4587 | Hi-Affi™ Rabbit Anti-ERBB2 Recombinant Antibody (clone TH100DS) | WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0098YC | Mouse Anti-ERBB2 Recombinant Antibody (clone E402) | Cyt | Mouse IgG1, κ |
| FAMAB-0099YC | Human Anti-ERBB2 Recombinant Antibody (clone CH402) | Cyt | Chimeric (mouse/human) IgG1 |
| FAMAB-0132CQ | Mouse Anti-ERBB2 Recombinant Antibody (clone SER4) | ELISA | Mouse IgG1 |
| HPAB-1111LY | Mouse Anti-ERBB2 Recombinant Antibody (HPAB-1111LY) | IHC, FuncS, FC | Mouse IgG |
| HPAB-1112LY | Human Anti-ERBB2 Recombinant Antibody (HPAB-1112LY) | ELISA | Chimeric (Mouse/Human) IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-468CQ | Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Timigutuzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-053 | Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Pertuzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-761 | Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Margetuximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-005 | Afuco™ Anti-ERBB2 ADCC Recombinant Antibody (Trastuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0079-YC-S(P) | Human Anti-ERBB2 Recombinant Antibody (clone HF2); scFv Fragment | FC, Inhib, ADCC, FuncS | Human scFv |
| HPAB-J0080-YC-S(P) | Human Anti-ERBB2 Recombinant Antibody (clone HF3); scFv Fragment | FC, Inhib, ADCC, FuncS | Human scFv |
| HPAB-J0081-YC-S(P) | Human Anti-ERBB2 Recombinant Antibody (clone HF4); scFv Fragment | FC, Inhib, ADCC, FuncS | Human scFv |
| HPAB-1265WJ-S(P) | Human Anti-ERBB2 Recombinant Antibody; scFv Fragment (HPAB-1265WJ-S(P)) | ELISA | Humanized scFv |
| FAMAB-0359JF-S(P) | Human Anti-ERBB2 Recombinant Antibody (clone FRc13); scFv Fragment | DB, ELISA, FuncS | Human scFv |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF049 | DRB1*01:01/Human HER2 (KVPIKWMALESILRRRF) MHC Monomer | MHC Multimer | |
| MHC-YF055 | DRB1*04:01/Human HER2 (KVPIKWMALESILRRRF) MHC Monomer | MHC Multimer | |
| MHC-YF478 | A*02:01/Human HER-2/neu (KIFGSLAFL) MHC Pentamer | FCM | |
| MHC-YF479 | A*02:01/Human HER-2/neu (ILHNGAYSL) MHC Pentamer | FCM | |
| MHC-YF480 | A*02:01/Human HER-2/neu (CLTSTVQLV) MHC Pentamer | FCM |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-1333WJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.