Recombinant Llama Anti-ERBB3 Single Domain Antibody (BCD090-M2) (CAT#: PABC-556)
This product is a recombinant Llama antibody that can recognize ErbB3. BCD090-M2 recognises erbB3, a receptor tyrosine kinase.
Specific Inquiry
SPR
Figure 1 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.
Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.
SPR
Figure 2 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.
Fitting of the measured response as a function of concentration of free BCD090-M2 in solution with a simple bimolecular equilibrium binding model gives KD=1 μM.
Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.
Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- Human ErbB3
- Species Reactivity
- Human
- Clone
- BCD090-M2
- Applications
- ELISA, SPR
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Surface Plasmon Resonance and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Erb-B2 Receptor Tyrosine Kinase 3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; Tyrosine Kinase-Type Cell Surface Receptor HER3; Human Epidermal Growth Factor Receptor 3; Proto-Oncogene-Like Protein C-ErbB-3; EC 2.7.10.1; HER3; Lethal Congenital Contracture Syndrome 2; P180-ErbB3; P45-SErbB3; P85-SErbB3; EC 2.7.10; MDA-BF-1; C-ErbB-3; C-ErbB3; ErbB3-S; ErbB-3; LCCS2
- Gene ID
- 2065
- UniProt ID
- P21860
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ERBB3"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1319z | Mouse Anti-ERBB3 Recombinant Antibody (clone 22C5) | ELISA, ICC, IF, WB | Mouse IgG1 |
| MOB-0309MZ | Recombinant Mouse Anti-Human ERBB3 Antibody (clone EAK-H4-IC) | IHC | Mouse antibody |
| HPAB-0286-YC | Mouse Anti-ERBB3 Recombinant Antibody (clone 1153) | ELISA, FuncS, FC | Mouse IgG |
| HPAB-0287-YC | Mouse Anti-ERBB3 Recombinant Antibody (clone 920104) | ELISA, FuncS, FC | Mouse IgG |
| HPAB-0288-YC | Mouse Anti-ERBB3 Recombinant Antibody (clone 1126) | ELISA, FuncS, FC | Mouse IgG |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L074E | HRGβ2-PE immunotoxin | Cytotoxicity assay, Functional assay |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-244CL | Anti-Human ERBB3 Recombinant Antibody (LJM716) | WB, ELISA | Antibody |
| TAB-062CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-062CT-F(E)) | ELISA, Inhib, FC | Human Fab |
| TAB-065CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-065CT-F(E)) | ELISA, FC | Human Fab |
| TAB-066CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-066CT-F(E)) | ELISA, Inhibion, FC | Human Fab |
| TAB-422CQ | Anti-Human ERBB3 Recombinant Antibody (Elgemtumab) | ELISA, IHC, FC, IP, IF, BL | IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-086 | Human Anti-ERBB3 Recombinant Antibody (clone KTN3379); scFv Fragment | ELISA, WB, IF, FuncS | Human scFv |
| PSBL-127 | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-127) | ELISA, WB, FuncS | Human scFv |
| PSBL-128 | Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-128) | WB, Block, FuncS | Mouse scFv |
| HPAB-1695-FY-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-1695-FY-F(E)) | ELISA | Human Fab |
| FAMAB-0047JF-S(P) | Human Anti-ERBB3 Recombinant Antibody (clone PM6); scFv Fragment | WB, ELISA, FuncS | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-059CT | Anti-Human HER3 Recombinant Antibody (LMAb3) | WB, ELISA, Inhibition, FC | Humanized antibody |
| TAB-063CT | Human Anti-ERBB3 Recombinant Antibody (TAB-063CT) | IF, WB, Inhib, ELISA | Humanized antibody |
| TAB-057CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-057CT-S(P)) | Inhibion, ELISA | Humanized scFv |
| TAB-058CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-058CT-S(P)) | WB, ELISA, Inhib | Human scFv |
| TAB-059CT-S(P) | Anti-Human HER3 Recombinant Antibody scFv Fragment (LMAb3) | WB, ELISA, Inhibition, FC | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-061CT | Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) | Inhib, ELISA | Chimeric (Rabbit/Human) antibody |
| TAB-061CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) | Inhib, ELISA | Human scFv |
| TAB-061CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) | Inhib, ELISA | Chimeric (Rabbit/Human) Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-064CT-F(E) | Mouse Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-064CT-F(E)) | ELISA, FC | Mouse Fab |
| TAB-067CT-F(E) | Anti-Human HER3 Recombinant Antibody Fab Fragment (5101) | ELISA, Inhibition, FC | |
| TAB-068CT-F(E) | Mouse Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-068CT-F(E)) | ELISA, Inhib, FC, WB | Mouse Fab |
| TAB-069CT-F(E) | Anti-Human HER3 Recombinant Antibody Fab Fragment (muHER3-8 ) | ELISA, Inhibition, FC | |
| TAB-071CT-F(E) | Anti-Human HER3 Recombinant Antibody Fab Fragment (SGP1) | IF, Inhibition, FC |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-738CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932) | Neut, IP | Mouse IgG1 |
| NEUT-739CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483) | FC, CyTOF®, ELISA, Neut | Mouse IgG1 |
| NEUT-740CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1019) | Neut | Human IgG1, κ |
| NEUT-741CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1020) | Neut | Human IgG1, κ |
| NEUT-742CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone M908) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1179 | Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) | ICC, IF, WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H21 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-422CQ | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
| AFC-TAB-189 | Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | Human IgG1, κ |
| AFC-TAB-H22 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| AFC-TAB-892 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0305-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 11G01); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-M0306-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 12A07); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-M0307-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 18H02); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-M0309-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 24C05); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-M0310-YC-F(E) | Human Anti-ERBB3 Recombinant Antibody (clone ch24C05); Fab Fragment | ELISA, Neut | Chimeric (mouse/human) Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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