Rabbit Anti-FANCB Recombinant Antibody (clone R05-8B7)
CAT#: VS3-FY1714
The R05-8B7 recombinant monoclonal antibody recognize human FANCB. It cross-reacts with mouse. This FANCB antibody was used in western blot analysis of FANCB in 3T3, Hela lysates. Western blot demonstrated that R05-8B7 recognized a target protein with a molecular weight of 98 kDa.
Gene Expression
Tested Data
Normal Tissue
Figure 1 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_A_7_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_A_8_4.jpg
Normal Tissue
Figure 5 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_A_3_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3124/8559_A_5_6.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181544-FANCB
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WB
Figure 1 Anti-FANCB Antibody (VS3-FY1714) in WB.
The FANCB expression in 3T3, Hela lysates were detected using the anti-FANCB by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human FANCB
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse FANCB
- Species Reactivity
- Human, Mouse
- Clone
- R05-8B7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 98 kDa, while the observed molecular weight stands at 98 kDa.
- Related Disease
- Fanconi Anemia, Complementation Group B and Intellectual Developmental Disorder, X-Linked, Syndromic, Pilorge Type
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Fanconi Anemia Complementation Group B; Fanconi Anemia-Associated Polypeptide Of 95 KDa; FAAP95; Fanconi Anemia Group B Protein; Protein FACB; EC 3.6.3.14
- Gene ID
- 2187
- UniProt ID
- Q8NB91
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Acetylation
- Protein Refseq
- XP_016884845.1; XP_047297876.1; XP_047297877.1; XP_047297878.1; XP_047297879.1
- Function
- DNA repair protein required for FANCD2 ubiquitination.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "FANCB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2183z | Mouse Anti-FANCB Recombinant Antibody (clone 36A10) | WB, ELISA, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2441 | Anti-FANCB Immunohistochemistry Kit | IHC |
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