Afuco™ Anti-FAP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-211) (CAT#: AFC-TAB-211)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to FAP. It is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_9_3.jpg

(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_8_4.jpg

(Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_7_5.jpg

(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_4_6.jpg

(Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_B_6_7.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078098-FAP
Specifications
- Immunogen
- A synthetic peptide derived from human Fibroblast activation protein, alpha.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF
- Conjugate
- Unconjugated
- Generic Name
- Sibrotuzumab
- Related Disease
- Unknown
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- humanized F19; FAP; fibroblast activation protein, alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA;
- Gene ID
- 2191
- UniProt ID
- Q12884
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Sibrotuzumab"
DrugMonitor™ Anti-Sibrotuzumab Antibody (VS-1224-YC1086)Sibrotuzumab is a humanized monoclonal antibody targeting fibroblast activation protein (FAP), used for cancer treatment. The DrugMonitor™ Anti-Sibrotuzumab Antibody (VS-1224-YC1086) is an anti-drug antibody (ADA) against Sibrotuzumab. This drug-based antibody is raised in mice immunized with the Sibrotuzumab. The anti-Sibrotuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Sibrotuzumab in samples.
See other products for "Fap"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2277z | Mouse Anti-FAP Recombinant Antibody (clone 36B12) | FC, IF, IP | Mouse IgG1 |
HPAB-0668-YJ | Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) | ELISA, Inhib, IHC, IF, FuncS | Human IgG1 |
VS-0723-WK245 | Rabbit Anti-FAP Recombinant Antibody (VS-0723-WK245) | ELISA, FC | Rabbit IgG |
VS7-HM929 | Mouse Anti-FAP Recombinant Antibody (clone 1H12F2) | IHC, FCM | Mouse IgG1 |
VS7-HM930 | Mouse Anti-FAP Recombinant Antibody (clone 5D9F6) | IHC, FCM | Mouse IgG1 |
Customer Reviews and Q&As
Effective at Low Concentrations
Quick and Reliable Delivery
Clear and Precise Results
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FuncS, Inhib, IP, ELISA
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, WB, FC
Application: ELISA, FuncS, Neut, IF, WB, EM, Inhib, IHC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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