Afuco™ Anti-FAP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-211)
CAT#: AFC-TAB-211
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to FAP. It is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP.






Specifications
- Immunogen
- A synthetic peptide derived from human Fibroblast activation protein, alpha.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF
- Conjugate
- Unconjugated
- Generic Name
- Sibrotuzumab
- Related Disease
- Unknown
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Q&As
-
What methods can I employ to optimize antibody-antigen binding?
A: Optimize incubation times and temperatures, and ensure proper sample preparation. Blocking and washing steps should also be fine-tuned.
-
Are there known limitations to using this antibody?
A: Check the datasheet for any known limitations, such as non-reactivity with certain species or incompatibility with specific detection methods.
-
How do I minimize proteolytic degradation of my samples?
A: Use protease inhibitors in your lysis buffer and keep samples cold during processing to minimize degradation.
View the frequently asked questions answered by Creative Biolabs Support.
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Biosimilar Overview
Please refer to Sibrotuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Sibrotuzumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Sibrotuzumab"
DrugMonitor™ Anti-Sibrotuzumab Antibody (VS-1224-YC1086)Sibrotuzumab is a humanized monoclonal antibody targeting fibroblast activation protein (FAP), used for cancer treatment. The DrugMonitor™ Anti-Sibrotuzumab Antibody (VS-1224-YC1086) is an anti-drug antibody (ADA) against Sibrotuzumab. This drug-based antibody is raised in mice immunized with the Sibrotuzumab. The anti-Sibrotuzumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Sibrotuzumab in samples.
See other products for "Fap"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-211 | Anti-Human FAP Recombinant Antibody (TAB-211) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-022WM | Human Anti-FAP Recombinant Antibody (TAB-022WM) | FC, ELISA | Human IgG1 |
TAB-024WM | Human Anti-FAP Recombinant Antibody (TAB-024WM) | IHC, ELISA, FC, IF | Human IgG1 |
TAB-022WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) | FC, ELISA | Human scFv |
TAB-024WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-024WM-S(P)) | ELISA, FC, IF | Human scFv |
TAB-022WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) | FC, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-150LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-151LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-152LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
Gly-153LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-153LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0170-CN | Human Anti-FAP Recombinant Antibody (HPAB-0170-CN) | ELISA, IF | Human IgG |
HPAB-0172-CN | Human Anti-FAP Recombinant Antibody (HPAB-0172-CN) | ELISA, IHC | Chimeric (mouse/human) IgG1, κ |
HPAB-0176-CN | Human Anti-FAP Recombinant Antibody (clone cF19) | ELISA, FC, IHC, IP, IF | Chimeric (mouse/human) IgG1 |
HPAB-0668-YJ | Human Anti-FAP Recombinant Antibody (HPAB-0668-YJ) | ELISA, Inhib, IHC, IF, FuncS | Human IgG1 |
HPAB-A1368-YJ | Mouse Anti-FAP Recombinant Antibody (clone F19) | ELISA, FuncS, RIA, IP, IF, IHC, IA, Block | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0170-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) | ELISA, IF | Human scFv |
HPAB-0176-CN-S(P) | Mouse Anti-FAP Recombinant Antibody (clone cF19); scFv Fragment | ELISA, FC, IHC, IP, IF | Mouse scFv |
HPAB-0668-YJ-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0668-YJ-S(P)) | ELISA, Inhib, IHC, IF, FuncS | Human scFv |
HPAB-2061-FY-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2061-FY-S(P)) | FC, ELISA, IF | Human scFv |
HPAB-2062-FY-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-2062-FY-S(P)) | FC, ELISA, IF | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0170-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) | ELISA, IF | Human Fab |
HPAB-0171-CN-F(E) | Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) | ELISA | Mouse Fab |
HPAB-0173-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) | ELISA | Humanized Fab |
HPAB-0175-CN-F(E) | Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment | ELISA, WB, FC, IHC, IP | Human Fab |
HPAB-0668-YJ-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0668-YJ-F(E)) | ELISA, Inhib, IHC, IF, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0619-CN | Recombinant Dromedary Anti-FAP Single Domain Antibody (HPAB-0619-CN) | ELISA | VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0661 | PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-CN0662 | APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-CN0663 | FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC | |
MHC-YF431 | A*02:01/Human FAP (GLFKCGIAV) MHC Pentamer | FCM | |
MHC-YF432 | A*02:01/Human FAP alpha (ALVCYGPGI) MHC Pentamer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0424-XY97 | AbPlus™ Anti-FAP Magnetic Beads (ESC14) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-FY118 | Human Anti-FAP (clone cF19) scFv-Fc Chimera | FC, IHC, IP | Human IgG1, scFv-Fc |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY813 | Anti-FAP Immunohistochemistry Kit | IHC | |
VS-0525-XY2444 | Anti-Human FAP Immunohistochemistry Kit | IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
VS13-YC379 | CytoStream™ Mouse Anti-FAP Recombinant Antibody (VS13-YC379) | IHC-P, FC, ELISA | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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