Rabbit Anti-FGF1 Recombinant Antibody (clone R02-9V5) (CAT#: VS3-XY3358)
The antibody is a recombinant rabbit antibody against human FGF1 (Fibroblast growth factor 1), which plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. The antibody also has cross-reactivity against mouse and rat FGF1. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3265/88_H7_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3265/88_H7_1_selected.jpg
Figure 2 High expression in kidney.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/ihc_selected.jpg
Figure 3 Low expression in liver.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_9_4_val_selected.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_7_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_7_5.jpg
Figure 5 Testis
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_6_6.jpg
(Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced.
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113578-FGF1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113578-FGF1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat FGF1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-9V5
- Applications
- WB, IHC-P
- Related Disease
- Common Peroneal Nerve Lesion; Overnutrition
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
- Gene ID
- 2246
- Long Name
- Fibroblast growth factor 1
- Cellular Localization
- Secreted, Cytoplasm, cell cortex, cytosol, Nucleus
- Post Translation Modifications
- In the nucleus, phosphorylated by PKC/PRKCD. (P05230-FGF1_HUMAN)
Modification sites at PhosphoSitePlus (P05230)
Modification sites at neXtProt (NX_P05230)
- Protein Refseq
- NP_000791.1; NP_001138364.1
- Function
- Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.
Functions as potent mitogen in vitro.
Acts as a ligand for FGFR1 and integrins.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "FGF1"
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IgG Antibody Products
Mouse Antibody Products
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Antibody Magnetic Beads
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2178z | Mouse Anti-FGF1 Recombinant Antibody (clone 32H5) | WB, ELISA, IF, IHC, IP | Mouse IgG1 |
| MOB-0726CT | Recombinant Mouse anti-Human FGF1 Monoclonal antibody (EML090) | ELISA, IHC-P, WB | |
| VS3-FY544 | Recombinant Rabbit Anti-FGF1 Antibody (clone R05-6A4) | WB | Rabbit IgG |
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