Rabbit Anti-FGF1 Recombinant Antibody (clone R02-9V5)
CAT#: VS3-XY3358
The antibody is a recombinant rabbit antibody against human FGF1 (Fibroblast growth factor 1), which plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. The antibody also has cross-reactivity against mouse and rat FGF1. It has been reported for use in Western Blot and Immunohistochemistry-Paraffin.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3265/88_H7_1_selected.jpg
Normal Tissue
Figure 2 High expression in kidney.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in liver.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_9_4_val_selected.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17519/39215_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113578-FGF1
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat FGF1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-9V5
- Applications
- WB, IHC-P
- Related Disease
- Common Peroneal Nerve Lesion; Overnutrition
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
Target
- Alternative Names
- AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha
- Gene ID
- 2246
- Long Name
- Fibroblast growth factor 1
- Cellular Localization
- Secreted, Cytoplasm, cell cortex, cytosol, Nucleus
- Post Translation Modifications
- In the nucleus, phosphorylated by PKC/PRKCD. (P05230-FGF1_HUMAN)
Modification sites at PhosphoSitePlus (P05230)
Modification sites at neXtProt (NX_P05230)
- Protein Refseq
- NP_000791.1; NP_001138364.1
- Function
- Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.
Functions as potent mitogen in vitro.
Acts as a ligand for FGFR1 and integrins.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "FGF1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2178z | Mouse Anti-FGF1 Recombinant Antibody (clone 32H5) | WB, ELISA, IF, IHC, IP | Mouse IgG1 |
| MOB-0726CT | Recombinant Mouse anti-Human FGF1 Monoclonal antibody (EML090) | ELISA, IHC-P, WB | |
| VS3-FY544 | Recombinant Rabbit Anti-FGF1 Antibody (clone R05-6A4) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-046WM | Anti-Human FGF1 Recombinant Antibody (1C9) | ELISA, IF, FC, IP, IHC | |
| TAB-046WM-S(P) | Anti-Human FGF1 Recombinant Antibody scFv Fragment (1C9) | ELISA, IF, FC, IP | |
| TAB-046WM-F(E) | Anti-Human FGF1 Recombinant Antibody Fab Fragment (1C9) | ELISA, IF, FC, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1291 | Hi-Affi™ Rabbit Anti-FGF1 Recombinant Antibody (clone DS1291AB) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY102 | AbPlus™ Anti-FGF1 Magnetic Beads (1C9) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY836 | Anti-FGF1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2512 | Anti-Human FGF1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2513 | Anti-Zebrafish FGF1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC114 | Recombinant Anti-FGF1 Eliminating Antibody, pH-Sensitive (1C9 var.) | Antigen-Sweeping In Vivo. | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC128 | SmartAb™ Recombinant Anti-FGF1 pH-dependent Antibody (Clone 1C9) | ELISA, IF, FC, IP, IHC | Mouse IgG |
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