Recombinant Mouse Anti-fHbp Antibody (JAR 1) (CAT#: FAMAB-0139CQ)
Recombinant Mouse Antibody clone JAR 1, which is specific to N. meningitidis fHbp. JAR 1 inhibited binding of fH to fHbp and had human complement-mediated bactericidal activity. It inhibited fH binding, had human complement-mediated bactericidal activity.
Specific Inquiry
WB
Figure 1 Expression of factor H–binding protein (fHbp) in outer membrane vesicle (OMV) preparations of representative isolates, as measured by Western blot analysis.
Monoclonal antibodies (MAbs) JAR 1 and JAR 5 were raised against fHbp variant 1 (v.1) (gene from strain MC58); MAb JAR 31 was raised against fHbp variant 3 (v.3) (gene from strain M1239), but it cross-reacts with fHbp variant 2 (v.2) and v.3 proteins. OMV from control strains included MC58 wt (fHbp v.1), MC58 fHbp knockout (∆fHbp) mutant, and RM1090 WT (fHbp v.2). The sequence type (ST) of each isolate is shown in parentheses. rfHbp, recombinant fHbp.
Beernink, P. T., Caugant, D. A., Welsch, J. A., Koeberling, O., & Granoff, D. M. (2009). Meningococcal factor H–binding protein variants expressed by epidemic capsular group A, W-135, and X strains from Africa. The Journal of infectious diseases, 199(9), 1360-1368.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG3
- Specificity
- N. meningitidis fHbp
- Species Reactivity
- N. meningitidis
- Clone
- JAR 1
- Applications
- ELISA, FC, WB, Inhib
- Related Disease
- Meningococcal disease
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot.
Target
- Alternative Names
- fhbP; Factor H-binding protein
- UniProt ID
- C6KHT4
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone JAR 1"
See other products for "fHbp"
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-070WM | Anti-N. meningitidis fHbp Recombinant Antibody (502) | ELISA, FC, Inhib | |
| TAB-070WM-S(P) | Anti-N. meningitidis fHbp Recombinant Antibody scFv Fragment (502) | WB, FC | |
| TAB-070WM-F(E) | Anti-N. meningitidis fHbp Recombinant Antibody Fab Fragment (502) | WB, FC |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-841CQ | Recombinant Mouse Anti-fhbP Antibody (JAR5) | ELISA, WB, BL | IgG2b, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0136CQ | Recombinant Human Anti-fHbp Antibody (chJAR 1) | ELISA, FC, Inhib | Chimeric (mouse/human) IgG1 |
| FAMAB-0137CQ | Recombinant Human Anti-fHbp Antibody (chJAR 3) | ELISA, WB, BL, FC | Chimeric (mouse/human) IgG1 |
| FAMAB-0138CQ | Recombinant Human Anti-fHbp Antibody (chJAR 5) | ELISA, WB, BL, FC | Chimeric (mouse/human) IgG1 |
| FAMAB-0140CQ | Recombinant Mouse Anti-fHbp Antibody (JAR 3) | ELISA, WB, Block, FC | Mouse IgG3 |
| HPAB-0023-WJ | Recombinant Mouse Anti-fHbp Antibody (JAR41) | ELISA, FC, DB, Inhib | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0136CQ-F(E) | Recombinant Human Anti-fHbp Antibody Fab Fragment (chJAR 1) | ELISA, FC, Inhib | Chimeric (mouse/human) Fab |
| FAMAB-0137CQ-F(E) | Recombinant Human Anti-fHbp Antibody Fab Fragment (chJAR 3) | ELISA, WB, BL, FC | Chimeric (mouse/human) Fab |
| FAMAB-0138CQ-F(E) | Recombinant Human Anti-fHbp Antibody Fab Fragment (chJAR 5) | ELISA, WB, BL, FC | Chimeric (mouse/human) Fab |
| FAMAB-0139CQ-F(E) | Recombinant Mouse Anti-fHbp Antibody Fab Fragment (JAR 1) | ELISA, FC, Inhib | Mouse Fab |
| FAMAB-0140CQ-F(E) | Recombinant Mouse Anti-fHbp Antibody Fab Fragment (JAR 3) | ELISA, WB, BL, FC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0139CQ-S(P) | Recombinant Mouse Anti-fHbp Antibody scFv Fragment (JAR 1) | ELISA, FC, Inhib | Mouse scFv |
| FAMAB-0140CQ-S(P) | Recombinant Mouse Anti-fHbp Antibody scFv Fragment (JAR 3) | ELISA, WB, BL, FC | Mouse scFv |
| HPAB-0023-WJ-S(P) | Recombinant Mouse Anti-fHbp Antibody scFv Fragment (JAR41) | ELISA, FC, DB, Inhib | Mouse scFv |
| HPAB-0766-WJ-S(P) | Recombinant Mouse Anti-fHbp Antibody scFv Fragment (JAR 64) | ELISA, WB | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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