Provided is a specific monoclonal antibody against the ED-B domain of Fibronectin, a maker of angiogenesis. ME4C binds to the ED-B domain with a dissociation constant in the nanomolar range and specifically stains tumors blood vessels of human and murine origin.
Figure 1 Immunohistochemical experiments with the antibody ME4C.
(A) A section of glioblastoma multiforme specimen. The typical glomerulus-like vascular structures are stained in red by the scFv (ME4C). Scale bar, 100 µm. (B) A section of SKMEL-28 human melanoma, grafted in a nude mouse, stained with scFv (ME4C). The antibody localises around vascular structures and proliferating cells. Scale bar, 50 µm.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-001CQ | Anti-Human FN1 Recombinant Antibody (MOR03255) | ELISA, Block, IHC | Human antibody |
TAB-002CQ | Anti-Human FN1 Recombinant Antibody (ME-4C) | ELISA, IHC | Human antibody |
TAB-003CQ | Anti-Human FN1 Recombinant Antibody (1C5) | ELISA, WB | Human antibody |
TAB-004CQ | Human Anti-FN1 Recombinant Antibody (TAB-004CQ) | ELISA, IHC, WB | Human IgG |
TAB-071WM-S(P) | Anti-Human FN1 Recombinant Antibody scFv Fragment (CGS-1) | ELISA, WB | Human Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-852CQ | Mouse Anti-FN1 Recombinant Antibody (clone HFN7.1) | ELISA, WB, IP, Block | Mouse IgG1 |
NEUT-853CQ | Mouse Anti-FN1 Recombinant Antibody (clone IST-9) | WB, RIA, ELISA, IHC-Fr, ICC, IF, Block, IHC-P | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1326 | Hi-Affi™ Rabbit Anti-FN1 Recombinant Antibody (clone DS1326AB) | IHC-Fr, IHC-P, IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1110-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1110-FY) | IHC | Human IgG |
HPAB-1111-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1111-FY) | IHC | Human IgG |
HPAB-1112-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1112-FY) | IHC | Human IgG |
HPAB-1113-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1113-FY) | IHC | Human IgG |
HPAB-1114-FY | Human Anti-FN1 Recombinant Antibody (HPAB-1114-FY) | IHC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1110-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1110-FY-S(P)) | IHC | Human scFv |
HPAB-1111-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1111-FY-S(P)) | IHC | Human scFv |
HPAB-1112-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1112-FY-S(P)) | IHC | Human scFv |
HPAB-1113-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1113-FY-S(P)) | IHC | Human scFv |
HPAB-1114-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1114-FY-S(P)) | IHC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1705-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02610); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1706-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02611); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1707-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02613); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-S0037-YC-S(P) | Human Anti-FN1 Recombinant Antibody (clone CGS-2); scFv Fragment | ELISA, IB, IHC | Human scFv |
HPAB-S0038-YC-S(P) | Human Anti-FN1 Recombinant Antibody (clone L19); scFv Fragment | ELISA, IF, IHC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NBD-0040-YJ-VHH | Camelid Anti-FN1 Recombinant Single Domain Antibody (NJB2) | ELISA, In vivo imaging | Camelid VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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