This product is a recombinant human antibody that recognizes FN1. The antibody was purified by affinity chromatography. It can be used in WB, ELISA, IHC-Fr.
Figure 1 Extradomain-B Fibronectin (EDB-FN) overexpression in invasive breast cancer.
Strong EDB-FN staining observed in adjacent tissue (NAT), and metastases in lung.
Vaidya, A., Wang, H., Qian, V., Gilmore, H., & Lu, Z. R. (2020). Overexpression of extradomain-B fibronectin is associated with invasion of breast cancer cells. Cells, 9(8), 1826.
Figure 2 Extradomain-B Fibronectin (EDB-FN) overexpression in invasive breast cancer.
3D cultures of the cancer cell lines stained with EDB-FN-specific ZD2-Cy5.5 probe show higher EDB-FN expression in the invasive cell lines than in MCF7 cells, demonstrating direct correlation with their invasive pattern.
Vaidya, A., Wang, H., Qian, V., Gilmore, H., & Lu, Z. R. (2020). Overexpression of extradomain-B fibronectin is associated with invasion of breast cancer cells. Cells, 9(8), 1826.
Figure 3 Depletion of EDB-FN and SRp55 in invasive TGF-β-treated and drug-resistant breast cancer cells reduces their invasion.
TGF-β-treated and drug-resistant MCF7 and MDA-MB-468 cells were treated with ECO/siNC (siN), ECO/siEDB (siE), and ECO/siSRSF6 (siS) nanoparticles at 100 nM [siRNA] and N/P = 10.
Vaidya, A., Wang, H., Qian, V., Gilmore, H., & Lu, Z. R. (2020). Overexpression of extradomain-B fibronectin is associated with invasion of breast cancer cells. Cells, 9(8), 1826.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-193 | Anti-Human Fibronectin Extra Domain-B Recombinant Antibody (Radretumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | [(scFv - heavy - kappa) - IGHE - CH4]2 |
TAB-071WM | Anti-Human FN1 Recombinant Antibody (CGS-1) | ELISA, WB | Human Antibody |
TAB-071WM-S(P) | Anti-Human FN1 Recombinant Antibody scFv Fragment (CGS-1) | ELISA, WB | Human Antibody |
TAB-001CQ-F(E) | Anti-Human FN1 Recombinant Antibody Fab Fragment (MOR03255) | ELISA, BL, IHC | Human antibody |
TAB-002CQ-F(E) | Anti-Human FN1 Recombinant Antibody Fab Fragment (ME-4C) | ELISA, IHC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0025MZ | Recombinant Mouse Anti-Human Fibronectin Antibody (clone C715M) | ELISA | Mouse antibody |
HPAB-0193-CN | Mouse Anti-FN1 Recombinant Antibody (HPAB-0193-CN) | ELISA, FC, IHC | Mouse IgG1 |
HPAB-0194-CN | Mouse Anti-FN1 Recombinant Antibody (HPAB-0194-CN) | ELISA, FC, IHC | Mouse IgG1 |
HPAB-0195-CN | Human Anti-FN1 Recombinant Antibody (HPAB-0195-CN) | ELISA, FC, IHC | Humanized IgG |
HPAB-0196-CN | Human Anti-FN1 Recombinant Antibody (HPAB-0196-CN) | ELISA, FC, IHC | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-852CQ | Mouse Anti-FN1 Recombinant Antibody (clone HFN7.1) | ELISA, WB, IP, Block | Mouse IgG1 |
NEUT-853CQ | Mouse Anti-FN1 Recombinant Antibody (clone IST-9) | WB, RIA, ELISA, IHC-Fr, ICC, IF, Block, IHC-P | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1326 | Hi-Affi™ Rabbit Anti-FN1 Recombinant Antibody (clone DS1326AB) | IHC-Fr, IHC-P, IHC-P, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0193-CN-F(E) | Mouse Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0193-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
HPAB-0194-CN-F(E) | Mouse Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0194-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
HPAB-0195-CN-F(E) | Human Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0195-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
HPAB-0196-CN-F(E) | Human Anti-FN1 Recombinant Antibody; Fab Fragment (HPAB-0196-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
HPAB-1110-FY-S(P) | Human Anti-FN1 Recombinant Antibody; scFv Fragment (HPAB-1110-FY-S(P)) | IHC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1705-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02610); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1706-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02611); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1707-FY-F(E) | Mouse Anti-FN1 Recombinant Antibody (clone MOR02613); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-S0037-YC-S(P) | Human Anti-FN1 Recombinant Antibody (clone CGS-2); scFv Fragment | ELISA, IB, IHC | Human scFv |
HPAB-S0038-YC-S(P) | Human Anti-FN1 Recombinant Antibody (clone L19); scFv Fragment | ELISA, IF, IHC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NBD-0040-YJ-VHH | Camelid Anti-FN1 Recombinant Single Domain Antibody (NJB2) | ELISA, In vivo imaging | Camelid VHH |
There are currently no Customer reviews or questions for FAMAB-1143CQ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.