Rabbit Anti-FOLH1 Recombinant Antibody (clone R04-6I6) (CAT#: VS3-XY3359)
The recombinant rabbit antibody is specific for FOLH1 (Folate hydrolase 1), which modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. FOLH1 also exhibits a dipeptidyl-peptidase IV type activity. The antibody specifically reacts with human FOLH1. It has been tested using Western Blot, Immunohistochemistry-Paraffin and Immunoprecipitation.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
(Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_7_5.jpg
Figure 2 Prostate
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1451/4354_A_2_5.jpg
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Figure 3 RNA cell line category: Cell line enhanced (HAP1, RPMI-8226, SK-BR-3, TIME, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000086205-FOLH1
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human FOLH1
- Species Reactivity
- Human
- Clone
- R04-6I6
- Applications
- WB, IHC-P, IP
- Related Disease
- Hyperhomocysteinemia; Prostate Cancer
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IP: 1/20
Target
- Alternative Names
- PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1
- Gene ID
- 2346
- UniProt ID
- Q04609
- Long Name
- Folate hydrolase 1
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. (Q04609-FOLH1_HUMAN)
The N-terminus is blocked. (Q04609-FOLH1_HUMAN)
Glycosylation at Asn76, Asn336, Asn51, Asn121, Asn140, Asn153, Asn195, Asn459, Asn476, and Asn638 (NX_Q04609 [NX_Q04609-1])
Modification sites at PhosphoSitePlus (Q04609)
Glycosylation from GlyGen (Q04609) 13 sites
- Protein Refseq
- XP_011518260.2; XP_016872921.1
- Function
- Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity.
Has a preference for tri-alpha-glutamate peptides.
In the intestine, required for the uptake of folate.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "FOLH1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-066 | Recombinant Anti-Human FOLH1 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-277CT | Anti-Human PSMA Therapeutic Single Domain Single Domain Antibody (TAB-277CT) | ELISA | Single domain antibody |
| HPAB-M0386-YC | Recombinant Camelid Anti-FOLH1 Single Domain Antibody (HPAB-M0386-YC) | ELISA | Camelid VHH |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018 | Anti-Human PMSA Recombinant Antibody (Capromab Pendetide) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-274CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-274CT) | FC, IA, IHC, Inhib, IB, IF, WB, ELISA | Mouse IgG2a |
| TAB-275CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-275CT) | ICC, FC, Block, IB, IF, IHC, Inhib, WB, ELISA | Mouse IgG1 |
| TAB-276CT | Mouse Anti-FOLH1 Recombinant Antibody (TAB-276CT) | IB, FC, IF, Inhib, WB, ELISA, IHC | Mouse IgG2b |
| TAB-278CT | Anti-Human PSMA Recombinant Antibody (L-186) | WB, ELISA, IP, IF |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G029E | Anti-FOLH1 immunotoxin D7 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G029D | Anti-FOLH1 immunotoxin D7 (scFv)-DT | Cytotoxicity assay, Function study |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1332 | Hi-Affi™ Rabbit Anti-FOLH1 Recombinant Antibody (clone DS1332AB) | IHC-P | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0184CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone 2A10); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0185CQ-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone YC058); Fab Fragment | FC, IHC | Human Fab |
| HPAB-1130WJ-F(E) | Mouse Anti-FOLH1 Recombinant Antibody (clone J415); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1154WJ-F(E) | Mouse Anti-FOLH1 Recombinant Antibody (clone E99); Fab Fragment | ELISA | Mouse Fab |
| HPAB-S0115-YC-F(E) | Human Anti-FOLH1 Recombinant Antibody (clone V5); Fab Fragment | ELISA | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0614-YC | Human Anti-FOLH1 Recombinant Antibody (HPAB-M0614-YC) | ELISA, FC, Cyt, FuncS | Human IgG |
| HPAB-1154WJ | Mouse Anti-FOLH1 Recombinant Antibody (clone E99) | ELISA | Mouse IgG |
| HPAB-S0115-YC | Human Anti-FOLH1 Recombinant Antibody (clone V5) | ELISA | Human IgG |
| MOB-0224F | Mouse Anti-FOLH1 Recombinant Antibody (MOB-0224F) | IHC-P, IF | Mouse IgG |
| MOB-0225F | Mouse Anti-FOLH1 Recombinant Antibody (MOB-0225F) | IHC-P, IF | Mouse IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-018 | Afuco™ Anti-FOLH1 ADCC Recombinant Antibody (Capromab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0677 | PE-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0678 | APC-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0679 | FITC-A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0680 | A*02:01/Human FOLH1 (MMNDQLMFL) MHC Tetramer | FCM, IHC | |
| MHC-CN0681 | PE-A*02:01/Human FOLH1 (SLFEPPPPG) MHC Tetramer | FCM, IHC |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0213-YC-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-J0213-YC-S(P)) | ELISA, IHC (0.3µg/mL), FuncS | Mouse scFv |
| HPAB-J0214-YC-S(P) | Mouse Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-J0214-YC-S(P)) | ELISA, IHC (0.3µg/mL) | Mouse scFv |
| HPAB-J0215-YC-S(P) | Human Anti-FOLH1 Recombinant Antibody; scFv Fragment (HPAB-J0215-YC-S(P)) | ELISA, WB, FuncS | Human scFv |
| HPAB-1248WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 3D8); scFv Fragment | ELISA | Human scFv |
| HPAB-1249WJ-S(P) | Human Anti-FOLH1 Recombinant Antibody (clone 4D4); scFv Fragment | ELISA | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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