Human Anti-FOXP2 Recombinant Antibody (clone RAB-S249)

Name: Human Anti-FOXP2 Recombinant Antibody (clone RAB-S249)
SKU: VS11-QX70
Rating: 5 (1 reviews)

CAT#: VS11-QX70

This product is a recombinant human antibody that recognizes FOXP2. This antibody can be used for the following applications: ELISA, IP, FC. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to DNA. It is expressed in the brain, heart, lungs and digestive system.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line RH-30

Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/1165_C5_2_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1679/if_selected.jpg

Normal Tissue Figure 3 IHC staining of human oral mucosa

Immunohistochemical staining of human oral mucosa shows moderate nuclear positivity in squamous epithelial cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_A_9_1_selected.jpg

Normal Tissue Figure 4 Endometrium 1

High expression in endometrium 1

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/383/612_B_4_3_val_selected.jpg

Normal Tissue Figure 5 Ovary

Ovarian stroma cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_A_4_7.jpg

Normal Tissue Figure 6 Cerebral cortex

Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_B_7_5.jpg

Normal Tissue Figure 7 Colon

Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_A_7_3.jpg

Normal Tissue Figure 8 Liver

Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_A_9_4.jpg

Normal Tissue Figure 9 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/382/564_A_8_5.jpg

RNA Expression Figure 10 RNA cell line category: Cell line enhanced (AF22, RH-30, THP-1)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128573-FOXP2

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Specifications

Immunogen
FOXP2 protein

Host Species
Human

Derivation
Human

Type
Human IgG1, κ

Specificity
Human FOXP2

Species Reactivity
Human

Clone
RAB-S249

Applications
ELISA, IP, FC

Conjugate
Unconjugated

Product Property

Clonality
Monoclonal

Purification
Protein A purified

Purity
>95% as determined by SDS-PAGE

Concentration
1 mg/mL (Please refer to the vial label for the specific concentration.)

Buffer
0.2 μm filtered solution in PBS

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Shipped at 4°C.

Target

Alternative Names
Forkhead Box Protein P2; SPCH1; TNRC10

Gene ID
93986

UniProt ID
O15409

Long Name
Forkhead box protein P2

Cellular Localization
Nucleoplasm

Function
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS11-QX70.pdf

MSDS

MSDS - VS11-QX70.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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See other products for "FOXP2"

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VS3-QX442	Mouse Anti-FOXP2 Recombinant Antibody (clone 533CT26.1.2)	WB	Mouse IgM

CAT	Product Name	Application	Type
VS3-XY727	Mouse Anti-FOXP2 Recombinant Antibody (clone 5C11A2)	ELISA, WB	Mouse IgG1
VS3-XY728	Mouse Anti-FOXP2 Recombinant Antibody (clone 5C11A8)	ELISA, WB	Mouse IgG1
VS7-HM967	Mouse Anti-FOXP2 Recombinant Antibody (clone 2G11B8)	WB, FCM	Mouse IgG1
VS7-HM968	Mouse Anti-FOXP2 Recombinant Antibody (clone CBL295HM)	WB, ELISA	Mouse IgG
VS7-HM969	Mouse Anti-FOXP2 Recombinant Antibody (clone CBL296HM)	WB, ELISA	Mouse IgG

CAT	Product Name	Application	Type
VS-0525-XY2640	Anti-FOXP2 Immunohistochemistry Kit	IHC
VS-0525-XY2641	Anti-Mouse FOXP2 Immunohistochemistry Kit	IHC

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