Human Anti-GABA-A synaptic receptor Recombinant Antibody (VS-0824-YJ42) (CAT#: VS-0824-YJ42)
CMG201 and CMG202 are fully human antibodies. CMG201 binds to GABA-A synaptic receptor α-γ interface and inhibits benzodiazepine-mediated potentiation of GABAA receptors. CMG202 binds to the two β-α subunit interfaces in the ECD of GABA-A synaptic receptor. It is only able to bind GABAA receptors containing the α1, but not α2-5 subunits. It has a potential to antagonize GABAA receptor activity.
| Sub Cat | Clone | Applications | Type | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0824-YJ4 | CMG201 | Inhib | Human IgG1 kappa | ||||||
| VS-0824-YJ5 | CMG202 | Antagonist | Human IgG1 lambda |
More Infomation
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (CACO-2, Karpas-707, RPMI-8226, SuSa, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113327-GABRG2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113327-GABRG2
Specifications
- Host Species
- Human
- Specificity
- Human GABA-A synaptic receptor
- Species Reactivity
- Human
- Related Disease
- Autoimmune encephalitis
Product Property
- Purity
- >95% as determined by SDS-PAGE or SEC-HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- γ-aminobutyric acid type A receptor; GABA-A synaptic receptor; GABAA synaptic receptor; GABA-A receptor; GABAA receptor
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2622z | Mouse Anti-GABRG2 Recombinant Antibody (clone 28A2) | ICC, IHC, IP | Mouse IgG2a |
| FAMAB-1353CQ | Mouse Anti-GABRG2 Recombinant Antibody (clone 10F10-C1-B8) | IP, WB, IF, IHC | Mouse IgG2b |
| VS-0522-LC102 | Rat Anti-Gabrg2 Recombinant Antibody (VS-0522-LC102) | IP, WB, IF, IHC | Rat IgG2b |
| VS-0522-LC103 | Rabbit Anti-Gabrg2 Recombinant Antibody (VS-0522-LC103) | IP, WB, IF, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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