AbPlus™ Anti-GAD2 Magnetic Beads (VS-0724-YC793)
CAT#: VS-0724-YC793
The AbPlus Anti-GAD2 Magnetic Beads (VS-0724-YC793) is an innovative affinity resin which is bound with anti-GAD2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of GAD2 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
Normal Tissue
Figure 2 Pancreas
Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136750-GAD2
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-GAD2 specific antibody
- Target
- GAD2
- Immunogen
- Recombinant human GAD65 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
- Alternative Names
- Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65;
- Gene ID
- 2572
- UniProt ID
- Q05329
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Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "GAD2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0421ZL | Rabbit anti-GAD2 polyclonal Antibody | WB | |
| MOB-2430MZ | Recombinant Mouse Anti-Rat GAD2 Antibody (clone HBE-7) | IHC-FoFr, IHC-Fr, IHC-P, WB | Mouse antibody |
| HPAB-1982-FY | Human Anti-GAD2 Recombinant Antibody (clone b78) | Inhib | Human IgG1, λ |
| VS3-WK875 | Mouse Anti-GAD2 Recombinant Antibody (VS3-WK875) | WB | Mouse IgG1 |
| VS-0223-WK24 | Rabbit Anti-GAD2 Recombinant Antibody (VS-0223-WK24) | WB, ICC, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1389 | Hi-Affi™ Rabbit Anti-GAD2 Recombinant Antibody (clone DS1389AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-F(E) | Human Anti-GAD2 Recombinant Antibody (clone b78); Fab Fragment | Inhib | Human Fab, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-S(P) | Human Anti-GAD2 Recombinant Antibody (clone b78); scFv Fragment | Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF030 | DRB1*04:01/Human GAD65 (IAFTSEHSHFSLK) MHC Monomer | MHC Multimer | |
| MHC-YF033 | DRB1*04:01/Human GAD65 (NFIRMVISNPAAT) MHC Monomer | MHC Multimer | |
| MHC-YF034 | DRB1*04:01/Human GAD65 (DVMNILLQYVVKSFDRSTKV) MHC Monomer | MHC Multimer | |
| MHC-YF035 | DRB1*04:01/Human GAD65 (KGMAALPRLIAFTSEHSHFS) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2716 | Anti-GAD2 Immunohistochemistry Kit | IHC |
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