AbPlus™ Anti-GAD2 Magnetic Beads (VS-0724-YC793) (CAT#: VS-0724-YC793)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-GAD2 specific antibody

• Target
• GAD2

• Immunogen
• Recombinant human GAD65 fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

• Alternative Names
• Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65;

• Gene ID
• 2572

• UniProt ID
• Q05329

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