Human Anti-GAD2 Recombinant Antibody (clone b78) (CAT#: HPAB-1982-FY)
This product is a recombinant antibody that recognizes GAD2. The monoclonal antibody b78 reacts with the epitope (AA 512–540) of GAD2.
Specific Inquiry
Inhib
Figure 1 Polyclonal and mAbs and their inhibition of GAD65 enzymatic activity.
Purified monoclonal and polyclonal Abs specific to GAD65 were tested for their capacity to inhibit GAD65 enzymatic activity. Results are shown as percent enzymatic activity related to GAD65 enzymatic activity in the absence of any Ab (100%). The figure represents three independent experiments, each conducted in duplicates. The error bars represent SEM.
Raju, R., Foote, J., Banga, J. P., Hall, T. R., Padoa, C. J., Dalakas, M. C., ... & Hampe, C. S. (2005). Analysis of GAD65 autoantibodies in Stiff-Person syndrome patients. The Journal of Immunology, 175(11), 7755-7762.
Specifications
- Immunogen
- Recombinant human GAD65.
- Host Species
- Human
- Type
- Human IgG1, λ
- Specificity
- Human GAD2
- Species Reactivity
- Human
- Clone
- b78
- Applications
- Inhib
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The GAD2 antibody has been reported in applications of Inhibition.
Target
- Alternative Names
- Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65
- Gene ID
- 2572
- UniProt ID
- Q05329
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone b78"
See other products for "GAD2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0421ZL | Rabbit anti-GAD2 polyclonal Antibody | WB | |
| MOB-131CQ | Mouse Anti-GAD2 Recombinant Antibody (clone YC068) | ELISA, ICC, IHC, FC, WB | Mouse IgG |
| VS1-YJ63 | Mouse Anti-GAD2 Recombinant Antibody (clone 144) | WB, FC, IP | Mouse IgG1 |
| VS1-YJ64 | Mouse Anti-GAD2 Recombinant Antibody (clone 144), PE | WB, FC, IP | Mouse IgG1 |
| VS3-WK146 | Mouse Anti-GAD2 Recombinant Antibody (clone G9-D12) | WB, ELISA | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1389 | Hi-Affi™ Rabbit Anti-GAD2 Recombinant Antibody (clone DS1389AB) | WB | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0697 | PE-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0698 | APC-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0699 | FITC-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0700 | DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0701 | PE-DRB1*04:01/Human GAD2 (NFIRMVISNPAAT) MHC Tetramer | FCM, IHC |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-F(E) | Human Anti-GAD2 Recombinant Antibody (clone b78); Fab Fragment | Inhib | Human Fab, λ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-S(P) | Human Anti-GAD2 Recombinant Antibody (clone b78); scFv Fragment | Inhib | Human scFv |
MHC Tetramer for Other Applications
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF030 | DRB1*04:01/Human GAD65 (IAFTSEHSHFSLK) MHC Monomer | MHC Multimer | |
| MHC-YF033 | DRB1*04:01/Human GAD65 (NFIRMVISNPAAT) MHC Monomer | MHC Multimer | |
| MHC-YF034 | DRB1*04:01/Human GAD65 (DVMNILLQYVVKSFDRSTKV) MHC Monomer | MHC Multimer | |
| MHC-YF035 | DRB1*04:01/Human GAD65 (KGMAALPRLIAFTSEHSHFS) MHC Monomer | MHC Multimer |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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