Afuco™ Anti-GD2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-731) (CAT#: AFC-TAB-731)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant chimeric (human/Mouse) antibody expressed in CHO binding to human GD2. It is a chimeric monoclonal antibody that induces antibody dependent cell-mediated cytotoxicity. It is intended as maintenance therapy (targeting minimal residual disease) for high risk neuroblastoma, administered after induction therapy, autologous stem cell transplantation and/or radiotherapy.
Specific Inquiry
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Chimeric
- Derivation
- Chimeric (mouse/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Trade name
- Unituxin
- Generic Name
- Dinutuximab
- Related Disease
- Neuroblastoma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Disialoganglioside GD2; Ganglioside G2; GD2
Related Resources
Please refer to Dinutuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Dinutuximab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Dinutuximab"
DrugMonitor™ Anti-Dinutuximab Antibody (VS-1224-YC361)Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody targeting GD2, used in immunotherapy strategies to treat neuroblastoma and prevent relapse. The DrugMonitor™ Anti-Dinutuximab Antibody (VS-1224-YC361) is an anti-drug antibody (ADA) against Dinutuximab. This drug-based antibody is raised in mice immunized with the Dinutuximab. The anti-Dinutuximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Dinutuximab in samples.
See other products for "GD2"
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Single Domain Antibody Products
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Neuroscience Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-770-sdAb | Recombinant Anti-Human GD2 VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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