Anti-GFAP (clone W24V101) Recombinant Antibody Coupled Liposome (VS-1024-FY103) (CAT#: VS-1024-FY103)

• Potential Clinical Applications
• Glioma

• Clone
• W24V101

• Antibody Type
• IgG

• Antibody Host
• Human

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant human monoclonal antibody that selectively interacts with human glial fibrillary acidic protein (GFAP). GFAP is an intermediate filament protein predominantly expressed in astrocytes, a type of glial cell in the central nervous system. The binding specificity of this antibody enables it to effectively target and identify GFAP in various biological samples.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• GFAP

• Introduction
• This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Alternative Names
• Glial Fibrillary Acidic Protein; Intermediate Filament Protein; ALXDRD

• Full Name
• Glial Fibrillary Acidic Protein

• Gene ID
• 2670

• UniProt ID
• P14136

• Sequence Similarities
• Belongs to the intermediate filament family.

• Cellular Localization
• Cytoplasm, Intermediate filament

• Post Translation Modifications
• Phosphorylated by PKN1.

• Protein Refseq
• NP_001124491.1; NP_001229305.1; NP_002046.1

• Function
• GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

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