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    Human Anti-GFRA3 Recombinant Antibody (clone Nadecnemab) (CAT#: VS-0723-WK32)

    This product is a human IgG4 antibody that recognizes human GFRA3, which can form a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Nadecnemab is recommended for flow cytometry (1/100) and ELISA (1/5000-1/10000) assays.

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    • Size:

    • Conjugation:

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    • Purity:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/247_B8_1_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_B_9_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_8_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_8_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_4_6.jpg
    Figure 7 Seminal vesicle
    Figure 7 Seminal vesicle
    (Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_8_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/20731/47965_A_9_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enriched (SH-SY5Y)
    Figure 9 RNA cell line category: Cell line enriched (SH-SY5Y)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000146013-GFRA3

    Specifications

    • Immunogen
    • Recombinant human GFRA3 protein
    • Host Species
    • Human
    • Type
    • Human IgG4
    • Specificity
    • Human GFRA3
    • Species Reactivity
    • Human
    • Clone
    • Nadecnemab
    • Applications
    • ELISA, FC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95%
    • Format
    • Lyophilized
    • Buffer
    • Lyophilized from sterile PBS (pH 7.4) with 5%-8% trehalose.
    • Preservative
    • No Preservative
    • Storage
    • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • ELISA: 1/5000-1/10000
      Flow Cytometry: 1/100

    Target

    • Alternative Names
    • GDNFR3
    • Long Name
    • GDNF Family Receptor Alpha 3

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "GFRA3"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Human Antibody Products IgG Antibody Products Rabbit Monoclonal Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-088CQ Human Anti-GFRA3 Recombinant Antibody (TAB-088CQ) ELISA, FC, RIA Human IgG
    TAB-087CQ-S(P) Human Anti-GFRA3 Recombinant Antibody; scFv Fragment (TAB-087CQ-S(P)) ELISA, FC, Block Human scFv
    TAB-088CQ-S(P) Human Anti-GFRA3 Recombinant Antibody; scFv Fragment (TAB-088CQ-S(P)) ELISA, FC, RIA Human scFv
    TAB-087CQ-F(E) Human Anti-GFRA3 Recombinant Antibody; Fab Fragment (TAB-087CQ-F(E)) ELISA, FC, Block Human Fab
    TAB-088CQ-F(E) Human Anti-GFRA3 Recombinant Antibody; Fab Fragment (TAB-088CQ-F(E)) ELISA, FC, RIA Human Fab

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