AbPlus™ Anti-GHRL Magnetic Beads (CP1A1)
CAT#: VS-0424-XY111
The AbPlus Anti-GHRL Magnetic Beads (CP1A1) is an innovative affinity resin which is bound with anti-GHRL specific antibody (CP1A1). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of GHRL protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 High expression in stomach 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14246/ihc_selected.jpg
Normal Tissue
Figure 2 Low expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14246/143315_A_8_4_val_selected.jpg
Normal Tissue
Figure 3 Stomach
Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14246/143315_A_1_1.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157017-GHRL
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-GHRL specific antibody (CP1A1)
- Target
- GHRL
- Immunogen
- Human acyl-ghrelin
- Target Species
- Human, Rat, Mouse
- Antibody Clone
- CP1A1
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.
- Alternative Names
- Acyl-ghrelin; GHRL; ghrelin/obestatin prepropeptide; MTLRP; appetite-regulating hormone; motilin-related peptide; ghrelin/obestatin preprohormone; growth hormone-releasing peptide; prepro-appetite regulatory hormone; ghrelin; growth hormone secretagogue receptor ligand
- Gene ID
- 51738
- UniProt ID
- Q9UBU3
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| HPAB-0187CQ-F(E) | Mouse Anti-GHRL Recombinant Antibody (clone MAb 3281); Fab Fragment | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
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| HPAB-0188CQ-F(E) | Mouse Anti-GHRL Recombinant Antibody (clone 2291); Fab Fragment | ELISA, FC | Mouse Fab |
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