Mouse Anti-GLS2 Recombinant Antibody (VS3-FY2719) (CAT#: VS3-FY2719)
The mouse anti-GLS2 recombinant monoclonal antibody has been developed to target GLS2. The calculated molecular weight of the antigen is 66.3 kDa. It shows capability of cross-reacting with human, mouse and rat. This monoclonal antibody is potential for conducting research on Juvenile Dermatitis Herpetiformis and Metabolic Acidosis. This monoclonal antibody can be used in Western Blot, Immunohistochemistry.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/ihc_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_B_7_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_8_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_9_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_6_6.jpg
Figure 7 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38608/80513_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (A-431, Daudi, Hep G2, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135423-GLS2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135423-GLS2
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Glutaminase 2 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 66.3 kDa.
- Related Disease
- Juvenile Dermatitis Herpetiformis and Metabolic Acidosis
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Target
- Alternative Names
- Glutaminase 2; Glutaminase 2 (Liver, Mitochondrial); L-Glutamine Amidohydrolase; EC 3.5.1.2; GLS; GA; Glutaminase Liver Isoform, Mitochondrial; Phosphate-Activated Glutaminase
- Gene ID
- 27165
- UniProt ID
- Q9UI32
- Sequence Similarities
- Belongs to the glutaminase family.
- Cellular Localization
- Mitochondrion
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- XP_005268854.1; XP_054227725.1; NP_001267725.1; NP_001267726.1; NP_001267727.1
- Function
- Plays an important role in the regulation of glutamine catabolism.
Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate.
Increases cellular anti-oxidant function via NADH and glutathione production.
May play a role in preventing tumor proliferation.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2539z | Mouse Anti-GLS2 Recombinant Antibody (clone 38A8) | ELISA, WB | Mouse IgG1, κ |
| VS3-WK1197 | Mouse Anti-GLS2 Recombinant Antibody (VS3-WK1197) | WB | Mouse IgG |
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