Rabbit Anti-GNAQ Recombinant Antibody (clone R08-2D5) (CAT#: VS3-FY1730)
The R08-2D5 recombinant monoclonal antibody specifically recognizes human GNAQ. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-P, IP. This GNAQ antibody has been teted positive by western blot analysis of GNAQ in K562, rat brain, C6, Hela lysates.
Specific Inquiry
WB
Figure 1 Anti-GNAQ Antibody (VS3-FY1730) in WB.
The GNAQ expression in K562, rat Brain, C6, Hela lysates were detected using the anti-GNAQ by western blot assay.
Specifications
- Immunogen
- Recombinant human GNAQ protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat GNAQ
- Species Reactivity
- Human, Rat
- Clone
- R08-2D5
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 42 kDa, while the observed molecular weight stands at 42 kDa.
- Related Disease
- Diseases associated with GNAQ include Sturge-Weber Syndrome and Capillary Malformations, Congenital
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunoprecipitation: 1/20
Target
- Alternative Names
- G Protein Subunit Alpha Q; Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide; Guanine Nucleotide-Binding Protein Alpha-Q; GAQ; Guanine Nucleotide-Binding Protein G(Q) Subunit Alpha; G-ALPHA-Q; CMC1; SWS
- Gene ID
- 2776
- UniProt ID
- P50148
- Sequence Similarities
- Belongs to the G-alpha family. G(q) subfamily.
- Cellular Localization
- Cell membrane, Golgi apparatus, Membrane, Nucleus
- Post Translation Modifications
- Palmitoylated by ZDHHC3 and ZDHHC7 (PubMed:19001095).
Palmitoylation occurs in the Golgi and participates in the localization of GNAQ to the plasma membrane (PubMed:19001095).
- Protein Refseq
- XP_047279195.1; XP_047279196.1; XP_054218730.1; XP_054218731.1; NP_002063.2
- Function
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Required for platelet activation. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "GNAQ"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2249z | Mouse Anti-GNAQ Recombinant Antibody (clone 10C4) | WB, ELISA, IF, IP | Mouse IgG1 |
| VS3-FY599 | Recombinant Rabbit Anti-GNAQ Antibody (clone R05-5D7) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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