Rabbit Anti-GNAQ Recombinant Antibody (clone R08-2D5) (CAT#: VS3-FY1730)
The R08-2D5 recombinant monoclonal antibody specifically recognizes human GNAQ. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-P, IP. This GNAQ antibody has been teted positive by western blot analysis of GNAQ in K562, rat brain, C6, Hela lysates.
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WB
Figure 1 Anti-GNAQ Antibody (VS3-FY1730) in WB.
The GNAQ expression in K562, rat Brain, C6, Hela lysates were detected using the anti-GNAQ by western blot assay.
Specifications
- Immunogen
- Recombinant human GNAQ protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat GNAQ
- Species Reactivity
- Human, Rat
- Clone
- R08-2D5
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 42 kDa, while the observed molecular weight stands at 42 kDa.
- Related Disease
- Diseases associated with GNAQ include Sturge-Weber Syndrome and Capillary Malformations, Congenital
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunoprecipitation: 1/20
Target
- Alternative Names
- G Protein Subunit Alpha Q; Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide; Guanine Nucleotide-Binding Protein Alpha-Q; GAQ; Guanine Nucleotide-Binding Protein G(Q) Subunit Alpha; G-ALPHA-Q; CMC1; SWS
- Gene ID
- 2776
- UniProt ID
- P50148
- Sequence Similarities
- Belongs to the G-alpha family. G(q) subfamily.
- Cellular Localization
- Cell membrane, Golgi apparatus, Membrane, Nucleus
- Post Translation Modifications
- Palmitoylated by ZDHHC3 and ZDHHC7 (PubMed:19001095).
Palmitoylation occurs in the Golgi and participates in the localization of GNAQ to the plasma membrane (PubMed:19001095).
- Protein Refseq
- XP_047279195.1; XP_047279196.1; XP_054218730.1; XP_054218731.1; NP_002063.2
- Function
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Required for platelet activation. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "GNAQ"
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IgG Antibodies
NHP Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2249z | Mouse Anti-GNAQ Recombinant Antibody (clone 10C4) | WB, ELISA, IF, IP | Mouse IgG1 |
| VS3-FY599 | Recombinant Rabbit Anti-GNAQ Antibody (clone R05-5D7) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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