AbPlus™ Anti-GRIA1 Magnetic Beads (CBACN-245) (CAT#: VS-0424-XY115)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-GRIA1 specific antibody (CBACN-245)

• Target
• GRIA1

• Immunogen
• Recombinant protein within human glutamate receptor 1 (AA 850 to the C-terminus)

• Target Species
• Human, Mouse, Rat

• Antibody Clone
• CBACN-245

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Alternative Names
• Glutamate Ionotropic Receptor AMPA Type Subunit 1; Glutamate Receptor, Ionotropic, AMPA 1; AMPA-Selective Glutamate Receptor 1; GluR-K1; GluR-1; GluR-A; GLUR1; GLUH1

• Gene ID
• 2890

• UniProt ID
• P42261

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