CytoStream™ Rabbit Anti-GRIN1 Recombinant Antibody (VS13-YC470)
CAT#: VS13-YC470
The CytoStream™ Rabbit Anti-GRIN1 Recombinant Antibody is specific for human, mouse and rat GRIN1. GRIN1, a critical NMDA receptor subunit, modulates synaptic plasticity and learning through glutamate receptor channels, impacting brain function via splice variant diversity. The anti-GRIN1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Normal Tissue
Figure 1 High expression in hippocampal formation
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_B_9_6_selected.jpg
Normal Tissue
Figure 2 Low expression in tonsil
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_A_4_8_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_B_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67773/168000_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (OE19, REH, RPMI-8226, SCLC-21H, SH-SY5Y, T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000176884-GRIN1
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Specifications
- Immunogen
- Recombinant human NMDAR1, aa 870-910.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat GRIN1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC-P, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunocytochemistry (ICC): 1/100-1/500
Immunofluorescence (IF): 1/100-1/500
Immunohistochemistry-paraffin (IHC-P): 1/50-1/800
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Glutamate Ionotropic Receptor NMDA Type Subunit 1; N-Methyl-D-Aspartate Receptor Subunit NR1; Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1; Glutamate [NMDA] Receptor Subunit Zeta-1; NMDAR1; NMD-R1; GluN1;
- Gene ID
- 2902
- UniProt ID
- Q05586
- Long Name
- Glutamate Ionotropic Receptor NMDA Type Subunit 1
- Cellular Localization
- Cell membrane; Postsynaptic cell membrane; Postsynaptic density
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "GRIN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2039z | Mouse Anti-GRIN1 Recombinant Antibody (clone 37D5) | WB, ICC, IF, IHC | Mouse IgG1 |
| HPAB-0025-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0025-CN) | ELISA, ICC, FC | Human IgG |
| HPAB-0026-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0026-CN) | ELISA, ICC, FC | Human IgG |
| HPAB-0027-CN | Human Anti-GRIN1 Recombinant Antibody (HPAB-0027-CN) | ELISA, ICC, FC | Human IgG |
| MRO-1098-CN | Rabbit Anti-GRIN1 Recombinant Antibody (clone JM11-26) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1510 | Rabbit Anti-GRIN1 Recombinant Antibody (clone DS1510AB) | WB, IP, IHC-P, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0025-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0025-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| HPAB-0026-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0026-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| HPAB-0027-CN-S(P) | Human Anti-GRIN1 Recombinant Antibody; scFv Fragment (HPAB-0027-CN-S(P)) | ELISA, ICC, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0025-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0025-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| HPAB-0026-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0026-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| HPAB-0027-CN-F(E) | Human Anti-GRIN1 Recombinant Antibody; Fab Fragment (HPAB-0027-CN-F(E)) | ELISA, ICC, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC673 | Recombinant Anti-GRIN1 Vesicular Antibody, EV Displayed (VS-0425-YC673) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2919 | Anti-Mouse GRIN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2920 | Anti-Rat GRIN1 Immunohistochemistry Kit | IHC |
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