Rabbit Anti-GSN Recombinant Antibody (clone R06-2I7) (CAT#: VS3-FY1726)

The R06-2I7 recombinant monoclonal antibody specifically recognizes human GSN. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-P, IP. This gelsolin antibody was used in western blot analysis of gelsolin in MCF-7, C6, Hela lysates.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Tested Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 Anti-GSN Antibody (VS3-FY1726) in WB.

Figure 1 Anti-GSN Antibody (VS3-FY1726) in WB.

The Gelsolin expression in MCF-7, C6, Hela lysates were detected using the anti-Gelsolin by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human gelsolin
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Rat GSN
  • Species Reactivity
  • Human, Rat
  • Clone
  • R06-2I7
  • Applications
  • Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 86 kDa, while the observed molecular weight stands at 86 kDa.
  • Related Disease
  • Amyloidosis, Finnish Type and Amyloidosis

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • Gelsolin; Actin-Depolymerizing Factor; Brevin; AGEL; ADF; Gelsolin (Amyloidosis, Finnish Type); Amyloidosis, Finnish Type
  • Cellular Localization
  • Amyloid, Cytoplasm, Cytoskeleton, Secreted
  • Post Translation Modifications
  • Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.
  • Function
  • Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed.
    Plays a role in ciliogenesis.

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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MOB-2035z Mouse Anti-GSN Recombinant Antibody (clone 33A5) WB, ELISA, ICC, IF, IHC Mouse IgG1, κ
MOB-2046MZ Recombinant Mouse Anti-Human GSN Antibody (clone HFM-53) FC, IHC-Fr, IHC-P, WB Mouse antibody
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VS3-FY625 Recombinant Rabbit Anti-GSN Antibody (clone R06-4B4) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG
VS7-HM1051 Mouse Anti-GSN Recombinant Antibody (clone 5E3B9) IHC, FCM Mouse IgG1

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