Rabbit Anti-GSN Recombinant Antibody (clone R06-2I7) (CAT#: VS3-FY1726)
The R06-2I7 recombinant monoclonal antibody specifically recognizes human GSN. It cross-reacts with rat. It is suitable for use in a variety of assays, including WB, IHC-P, IP. This gelsolin antibody was used in western blot analysis of gelsolin in MCF-7, C6, Hela lysates.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Anti-GSN Antibody (VS3-FY1726) in WB.
The Gelsolin expression in MCF-7, C6, Hela lysates were detected using the anti-Gelsolin by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human gelsolin
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat GSN
- Species Reactivity
- Human, Rat
- Clone
- R06-2I7
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 86 kDa, while the observed molecular weight stands at 86 kDa.
- Related Disease
- Amyloidosis, Finnish Type and Amyloidosis
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunoprecipitation: 1/20
Target
- Alternative Names
- Gelsolin; Actin-Depolymerizing Factor; Brevin; AGEL; ADF; Gelsolin (Amyloidosis, Finnish Type); Amyloidosis, Finnish Type
- Gene ID
- 2934
- UniProt ID
- P06396
- Cellular Localization
- Amyloid, Cytoplasm, Cytoskeleton, Secreted
- Post Translation Modifications
- Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.
- Protein Refseq
- XP_005252001.1; XP_011516887.1; XP_011516896.1; XP_016870134.1; XP_047279221.1
- Function
- Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed.
Plays a role in ciliogenesis.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GSN"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2035z | Mouse Anti-GSN Recombinant Antibody (clone 33A5) | WB, ELISA, ICC, IF, IHC | Mouse IgG1, κ |
MOB-2046MZ | Recombinant Mouse Anti-Human GSN Antibody (clone HFM-53) | FC, IHC-Fr, IHC-P, WB | Mouse antibody |
MRO-0645-CN | Rabbit Anti-GSN Recombinant Antibody (clone JB36-68) | WB, IF, IHC, FC | Rabbit IgG |
VS3-FY625 | Recombinant Rabbit Anti-GSN Antibody (clone R06-4B4) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
VS7-HM1051 | Mouse Anti-GSN Recombinant Antibody (clone 5E3B9) | IHC, FCM | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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