Camelid Anti-GSN Recombinant Single Domain Antibody (NBD-0041-YJ-VHH)
CAT#: NBD-0041-YJ-VHH
This product is a recombinant Llama single domain antibody that recognizes Human GSN. The sdAb's protective effect is based on the enhancement of the thermodynamic stability of different G2 mutants (D187N, G167R and N184K).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to actin filaments.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16728/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in dendritic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54026/138110_A_5_8_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10823/24834_A_8_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10823/24834_B_7_5.jpg
Normal Tissue
Figure 5 Lung
Alveolar cells type I Staining: Low Intensity: Weak Quantity: 75%-25% Alveolar cells type I I Staining: Low Intensity: Weak Quantity: 75%-25% Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Macrophages Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10823/24834_A_2_4.jpg
Normal Tissue
Figure 6 Colon
Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75% Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25% Peripheral nerve/ganglion Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10823/24834_A_8_3.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, HaCaT)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148180-GSN
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Specifications
- Immunogen
- Human recombinant gelsolin.
- Host Species
- Camelid
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- NBD-0041-YJ-VHH
- Applications
- ELISA, IF, Inhib
- Related Disease
- AGel amyloidosis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This sdAb has been reported for use in Enzyme-linked Immunosorbent Assay, Immunofluorescence, Inhibition.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "GSN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2035z | Mouse Anti-GSN Recombinant Antibody (clone 33A5) | WB, ELISA, ICC, IF, IHC | Mouse IgG1, κ |
| MOB-2046MZ | Recombinant Mouse Anti-Human GSN Antibody (clone HFM-53) | FC, IHC-Fr, IHC-P, WB | Mouse antibody |
| MRO-0645-CN | Rabbit Anti-GSN Recombinant Antibody (clone JB36-68) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-FY625 | Recombinant Rabbit Anti-GSN Antibody (clone R06-4B4) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
| VS7-HM1051 | Mouse Anti-GSN Recombinant Antibody (clone 5E3B9) | IHC, FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-071 | Recombinant Anti-Mouse Gsn VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| PNBL-100 | Recombinant Anti-GSN VHH Single Domain Antibody (PNBL-100) | BL, ELISA, IP, IHC, WB | Llama VHH |
| HPAB-0342CQ | Recombinant Llama Anti-GSN Single Domain Antibody (HPAB-0342CQ) | ELISA, IHC, IF, IP, Pull down, FuncS | Llama VHH |
| HPAB-0343CQ | Recombinant Llama Anti-GSN Single Domain Antibody (HPAB-0343CQ) | ELISA, IHC, IF, IP, Pull down, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1527 | Rabbit Anti-GSN Recombinant Antibody (clone DS1527AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY784 | Mouse Anti-GSN Recombinant Antibody (clone 328CT2.2.1) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2946 | Anti-GSN Immunohistochemistry Kit | IHC | |
| VS-0525-XY2947 | Anti-Mouse GSN Immunohistochemistry Kit | IHC | |
| VS-0525-XY2948 | Anti-Bovine GSN Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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