AbPlus™ Anti-GYPC Magnetic Beads (VS-0724-YC1189) (CAT#: VS-0724-YC1189)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-GYPC specific antibody

• Target
• GYPC

• Immunogen
• Recombinant human Glycophorin C, aa 1-57.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

• Alternative Names
• Glycophorin C (Gerbich Blood Group); Sialoglycoprotein D; Glycoprotein Beta; Glycoconnectin; Glycophorin-D; PAS-2; GPD; GPC; GE:GPC:GPD:GYPD;

• Gene ID
• 2995

• UniProt ID
• P04921

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