AbPlus™ Anti-GYPC Magnetic Beads (VS-0724-YC1189)

CAT#: VS-0724-YC1189

The AbPlus Anti-GYPC Magnetic Beads (VS-0724-YC1189) is an innovative affinity resin which is bound with anti-GYPC specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of GYPC protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line HEL Figure 2 IF staining of human cell line K-562 Figure 3 IF staining of human cell line SK-MEL-30 Figure 4 Cerebral cortex Figure 5 Colon Figure 6 Testis Figure 7 Lymph node Figure 8 RNA cell line category: Cell line enhanced (HHSteC, K-562, SK-MEL-30, U-266/70)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-GYPC specific antibody
  • Target
  • GYPC
  • Immunogen
  • Recombinant human Glycophorin C, aa 1-57.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
  • Alternative Names
  • Glycophorin C (Gerbich Blood Group); Sialoglycoprotein D; Glycoprotein Beta; Glycoconnectin; Glycophorin-D; PAS-2; GPD; GPC; GE:GPC:GPD:GYPD;
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