Mouse Anti-H3C1 Recombinant Antibody (clone 1C2)
CAT#: VS7-0425-WR45
This product is a mouse IgG recombinant antibody that binds to human H3C1. The antibody 1C2 can be used for WB assay. It also cross-reacts with rat and mouse.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_8_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Pachytene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Peritubular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Preleptotene spermatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000275714-H3C1
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Specifications
- Immunogen
- Synthetic Histone H3 (Mono Methyl Lys79) peptide
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human H3C1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- 1C2
- Molecule Class
- Structure Molecule
- Applications
- WB
- Conjugate
- Unconjugated
- Related Disease
- Glioma (GLM)
Product Property
- Clonality
- Monoclonal
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.02% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:1000 - 1:3000
Target
- Alternative Names
- H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A
- Gene ID
- 8350
- UniProt ID
- P68431
- Long Name
- H3 clustered histone 1
- Cellular Localization
- Chromosome; Nucleosome core; Nucleus
- Post Translation Modifications
- Acetylation; ADP-ribosylation; Citrullination; Hydroxylation; Lipoprotein; Methylation; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_066298
- Function
- DNA-binding
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3031 | Anti-H3C1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3032 | Anti-Mouse H3C1 Immunohistochemistry Kit | IHC | |
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